Depression is a common neuropsychiatric manifestation among Alzheimer's disease (AD)
patients. It may compromise everyday activities and lead to a faster cognitive decline as well …

Major depressive disorders (MDD) are among the most debilitating diseases worldwide and
occur with a high prevalence in elderly individuals. Neurodegenerative diseases (in …

Background: Depressive symptoms often co-occur with Alzheimer's disease (AD) and can
impact neuropsychological test results. In early stages of AD, disentangling cognitive …

Alzheimer's disease (AD) studies in cognitively normal (CN) older adults age≥ 65 suggest
depression is associated with molecular biomarkers (imaging and cerebrospinal fluid [CSF]) …

Depression and dementia, in particular Alzheimer's disease (AD), are critically important
issues in the mental health of old age. Both conditions apparently reduce quality of life and …

Depression occurs with a high prevalence of up to 50% in patients with Alzheimer's disease
(AD) and increases the caregivers' burden. Depression symptoms can precede clinical …

This review provides the rationale and background for the development of diagnostic criteria
for depression of Alzheimer disease (AD), including risk factors and neurobiological …

Introduction Understanding the relationship between different depression presentations and
cognitive outcome may elucidate high‐risk sub‐groups for cognitive decline. Methods In this …

The pathophysiology of negative affect states in older adults is complex, and a host of
central nervous system and peripheral systemic mechanisms may play primary or …

Late-life depression is frequently associated with cognitive impairment. Depressive
symptoms are often associated with or even precede a dementia syndrome. Moreover …