Intracellular and extracellular cytokines in A549 cells and THP1 cells exposed to cigarette smoke

A Holownia, P Wielgat, E Rysiak, JJ Braszko - Respiratory Medicine and …, 2016 - Springer
Cigarette smoke (CS) activates inflammatory cells and increases cytokine levels producing
local and systemic inflammation. To assess changes in intracellular and extracellular …

Comparison of two in vitro models of cigarette smoke exposure

J St-Laurent, LI Proulx, LP Boulet… - Inhalation …, 2009 - Taylor & Francis
Cigarette smoke is associated with a high morbidity and mortality, and affects particularly the
respiratory tract. Various in vitro models have been developed to study the effects of …

Differential effects of cigarette smoke on oxidative stress and proinflammatory cytokine release in primary human airway epithelial cells and in a variety of transformed …

A Kode, SR Yang, I Rahman - Respiratory research, 2006 - Springer
Background Cigarette smoke mediated oxidative stress and inflammatory events in the
airway and alveolar epithelium are important processes in the pathogenesis of smoking …

Dose-dependent cigarette smoking-related inflammatory responses in healthy adults

WG Kuschner, A D'alessandro… - European Respiratory …, 1996 - Eur Respiratory Soc
The aim of this study was to determine the dose-response relationship between cigarette
smoke exposure and pulmonary cell and cytokine concentrations in bronchoalveolar lavage …

Kinetic analysis of cytokine response to cigarette smoke condensate by human endothelial and monocytic cells

BK Nordskog, WR Fields, GM Hellmann - Toxicology, 2005 - Elsevier
Atherosclerosis is generally considered an inflammatory disease characterized by the
accumulation of lipid in large and medium elastic arteries. Individuals who smoke are at …

Acute effects of cigarette smoke on inflammation and oxidative stress: a review

H van der Vaart, DS Postma, W Timens… - Thorax, 2004 - thorax.bmj.com
Compared with the effects of chronic smoke exposure on lung function and airway
inflammation, there are few data on the acute effects of smoking. A review of the literature …

Acute effects of cigarette smoking on inflammation in healthy intermittent smokers

H Van der Vaart, DS Postma, W Timens… - Respiratory …, 2005 - Springer
Background Chronic smoking is the main risk factor for chronic obstructive pulmonary
disease. Knowledge on the response to the initial smoke exposures might enhance the …

In vitro acute effects of tobacco smoke on tumor necrosis factor a and interleukin-6 production by alveolar macrophages

VÉR Dubar, P Gosset, C Aerts, C Voisin… - Experimental lung …, 1993 - Taylor & Francis
Tobacco smoke is a usual form of oxidant aggression present in the domestic environment.
In the present study, the in vitro acute effects of a 2-cigarette smoke gas phase were …

Innate immune processes are sufficient for driving cigarette smoke–induced inflammation in mice

FM Botelho, GJ Gaschler, S Kianpour… - American journal of …, 2010 - atsjournals.org
The objective of this study was to characterize the impact of cigarette smoke exposure on
lung immune and inflammatory processes. BALB/c and C57BL/6 mice were exposed to …

Acute effects of smoking and high experimental exposure to environmental tobacco smoke (ETS) on the immune system

S Hockertz, A Emmendörffer, G Scherer… - Cell biology and …, 1994 - Springer
Controversial results have been published on the immune response to cigarette smoking
while the effects of exposure to environmental tobacco smoke (ETS) have not yet been …