Background Currently, due to synergy enhancement of anti‐tumor effects and potent
stimulation of abscopal effects, combination therapy with irradiation and programmed cell …

Simple Summary Combination of radiotherapy and immunotherapy to antagonize tumors is
one of hotspot issues currently. Immunotherapy can effectively alleviate the non-lasting …

Background Radiotherapy (RT) has been shown to stimulate an antitumor immune response
in irradiated tumors as well as unirradiated distant sites (abscopal effect). Previous studies …

Ionising radiation (IR) may harm cancer cells through a rare indirect out-of-field
phenomenon described as the abscopal effect. Increasing evidence demonstrates that …

The tumor-draining lymph nodes (TDLNs) are the primary sites of the development of anti-
tumor immunity. Primary tumor irradiation promotes 'radio-vaccination'by enhancing the …

Radiotherapy (RT) is used routinely as a standard treatment for more than 50% of patients
with malignant tumors. The abscopal effect induced by local RT, which is considered as a …

Lymphodepletion before adoptive cell transfer (ACT)-based immunotherapies can enhance
anti-tumor responses by augmenting innate immunity, by increasing access to homeostatic …

Background Radiation therapy (rt) is a longstanding treatment modality for cancer. In
addition, immune checkpoint blockade has been a significant development in the field of …

T-cell adoptive immunotherapy for stringent murine tumor models, such as intracranial, sc, or
advanced pulmonary metastases, routinely uses lymphodepletive conditioning regimens …

Radiotherapy is one of the main treatment strategies used in cancer. Aside from the local
control of the disease, which is mediated by a direct cytotoxic effect on tumor cells …