Mosaic loss of the Y chromosome (mLOY), a type of clonal hematopoiesis, is the most
frequent chromosomal alteration observed in leukocytes of aging men. mLOY is a putative …

Mosaic loss of the Y chromosome (mLOY) in peripheral leukocytes is a somatic event in
which a fraction of leukocytes have lost the entire Y chromosome. The frequency of mLOY …

Background: Genomic instability is a significant hallmark of aging and has a major impact on
aging biology. Mosaic loss of chromosome Y (mLOY) in blood cells is a common …

Mosaic loss of Y chromosome (mLOY) is the most frequently detected somatic copy number
alteration in leukocytes of men. In this study, we investigate blood cell counts as a potential …

Mosaic loss of the Y chromosome (mLOY) is the most commonly reported large structural
somatic event. Previous studies have indicated age and cigarette smoking increase the risk …

Background Mosaic loss of chromosome Y (LOY) in leukocytes is the most prevalent somatic
aneuploidy in aging humans. Men with LOY have increased risks of all-cause mortality and …

Mosaic loss of chromosome Y (LOY) in circulating white blood cells is the most common
form of clonal mosaicism, yet our knowledge of the causes and consequences of this is …

Background Although age-related loss of chromosome Y (LOY) in normal hematopoietic
cells is a well-known phenomenon, the phenotypic consequences of LOY have been …

Mosaic loss of chromosome Y (LOY) in circulating white blood cells is the most common
form of clonal mosaicism, yet our knowledge of the causes and consequences of this is …

Incidence and mortality for sex-unspecific cancers are higher among men, a fact that is
largely unexplained,. Furthermore, age-related loss of chromosome Y (LOY) is frequent in …