[PDF][PDF] Brief overview of various approaches to enhance drug solubility

ML Hart, DP Do, RA Ansari, SAA Rizvi - J. Dev. Drugs, 2013 - researchgate.net
Aqueous solubility is one of the most influencing factors when it comes to bioavailability of
the drugs. It is the main key for drug effectiveness and enhancing water solubility, which …

Techniques to enhance solubility of hydrophobic drugs: an overview

DC Vimalson - Asian Journal of Pharmaceutics (AJP), 2016 - asiapharmaceutics.info
The solubility enhancement process of hydrophobic drugs plays a key role in the formulation
development to achieve the bioavailability and therapeutic action of the drug at the target …

Pharmaceutical methods for enhancing the dissolution of poorly water-soluble drugs

T Mahmood, RM Sarfraz, A Ismail, M Ali… - ASSAY and Drug …, 2023 - liebertpub.com
Low water solubility is the main hindrance in the growth of pharmaceutical industry.
Approximately 90% of newer molecules under investigation for drugs and 40% of novel …

[HTML][HTML] A review on solubility enhancement methods for poorly water-soluble drugs

A Ainurofiq, DS Putro, DA Ramadhani… - Journal of Reports in …, 2021 - journals.lww.com
One of the most important parameters in pharmacy is drug solubility. Solubility affects the
efficacy of a drug. Drug solubility has an important role in determining the concentration of a …

Various techniques enhancing bioavailabilty of poorly water soluble drugs

AK Thakur, N Nirmala, SL Harikumar - Journal of Drug Delivery and …, 2013 - jddtonline.info
A drug administered in solution form immediately available for absorption and efficiently
absorbed than the same amount of drug administered in a tablet or capsule form. Solubility …

[PDF][PDF] Solubility and dissolution enhancement: an overview

VR Babu, SH Areefulla, V Mallikarjun - J Pharm Res, 2010 - Citeseer
Poorly water soluble compounds have solubility and dissolution related bioavailability
problems. The dissolution rate is directly proportional to solubility of drugs. Drugs with low …

[PDF][PDF] Review on solubility enhancement techniques for hydrophobic drugs

A Kumar, SK Sahoo, K Padhee, PS Kochar… - Pharmacie …, 2011 - researchgate.net
Among all newly discovered chemical entities about 40% drugs are lipophillic and fail to
reach market due to their poor aqueous solubility. For orally administered drugs solubility is …

[PDF][PDF] An overview on solubility enhancement techniques for poorly soluble drugs and solid dispersion as an eminent strategic approach

S Jatwani, AC Rana, G Singh… - International journal of …, 2012 - researchgate.net
Solubility is an important parameter to achieve desired concentration of drug in systemic
circulation for pharmacological response to be shown. Among all newly discovered …

[PDF][PDF] Techniques to improve the solubility of poorly soluble drugs.

JN Patel, DM Rathod, NA Patel… - International Journal of …, 2012 - researchgate.net
A drug administered in solution form immediately available for absorption and efficiently
absorbed than the same amount of drug administered in a tablet or capsule form. Solubility …

[HTML][HTML] Advancement in solubilization approaches: a step towards bioavailability enhancement of poorly soluble drugs

L Kumari, Y Choudhari, P Patel, GD Gupta, D Singh… - Life, 2023 - mdpi.com
A drug's aqueous solubility is defined as the ability to dissolve in a particular solvent, and it
is currently a major hurdle in bringing new drug molecules to the market. According to some …