Current hurdles to the translation of nanomedicines from bench to the clinic
S Đorđević, MM Gonzalez, I Conejos-Sánchez… - Drug delivery and …, 2022 - Springer
The field of nanomedicine has significantly influenced research areas such as drug delivery,
diagnostics, theranostics, and regenerative medicine; however, the further development of …
diagnostics, theranostics, and regenerative medicine; however, the further development of …
Facilitating the translation of nanomedicines to a clinical product: challenges and opportunities
V Agrahari, V Agrahari - Drug Discovery Today, 2018 - Elsevier
Highlights•Clinical translation and commercialization challenges of nanomedicine products.•
Manufacturing or scale-up, characterization, safety, stability and efficacy …
Manufacturing or scale-up, characterization, safety, stability and efficacy …
Characterization of nanomedicines: A reflection on a field under construction needed for clinical translation success
JB Coty, C Vauthier - Journal of controlled release, 2018 - Elsevier
The nanotechnology revolution offers many expectations for the improvement of medicine
treatments. At present, nanomedicine (NM) development is hampered by methodological …
treatments. At present, nanomedicine (NM) development is hampered by methodological …
Challenges in nanomedicine clinical translation
JM Metselaar, T Lammers - Drug delivery and translational research, 2020 - Springer
New nanomedicine formulations and novel applications of nanomedicinal drugs are
reported on an almost daily basis. While academic progress and societal promise continue …
reported on an almost daily basis. While academic progress and societal promise continue …
Clinical translation of nanomedicines: Challenges, opportunities, and keys
Despite the massive interest and recent developments in the field of nanomedicine, only a
limited number of formulations have found their way to the clinics. This shortcoming reveals …
limited number of formulations have found their way to the clinics. This shortcoming reveals …
Translational formulation of nanoparticle therapeutics from laboratory discovery to clinical scale
Background “Nanomedicine” is the application of purposely designed nano-scale materials
for improved therapeutic and diagnostic outcomes, which cannot be otherwise achieved …
for improved therapeutic and diagnostic outcomes, which cannot be otherwise achieved …
Nanomedicines: from bench to bedside and beyond
H Havel, G Finch, P Strode, M Wolfgang, S Zale… - The AAPS journal, 2016 - Springer
Advancing nanomedicines from concept to clinic requires integration of new science with
traditional pharmaceutical development. The medical and commercial success of …
traditional pharmaceutical development. The medical and commercial success of …
Evolution and clinical translation of drug delivery nanomaterials
With the advent of technology, the role of nanomaterials in medicine has grown
exponentially in the last few decades. The main advantage of such materials has been …
exponentially in the last few decades. The main advantage of such materials has been …
[HTML][HTML] Delivering the power of nanomedicine to patients today
The situation of the COVID-19 pandemic reminds us that we permanently need high-value
flexible solutions to urgent clinical needs including simplified diagnostic technologies …
flexible solutions to urgent clinical needs including simplified diagnostic technologies …
Nanomedicine (s) under the microscope
R Duncan, R Gaspar - Molecular pharmaceutics, 2011 - ACS Publications
Depending on the context, nanotechnologies developed as nanomedicines (nanosized
therapeutics and imaging agents) are presented as either a remarkable technological …
therapeutics and imaging agents) are presented as either a remarkable technological …