Naloxone is a specific, high affinity opioid antagonist that has been used to treat suspected
or confirmed overdose for more than 40 years. Naloxone use was initially confined to an …

Overdose due to opioid abuse is an ever increasing problem, especially in the United
States, with the last few years seeing a dramatic rise in the number of synthetic opioid …

Background The USA has recently entered the third decade of the opioid epidemic. Opioid
overdose deaths reached a new record of over 74,000 in a 12-month period ending April …

Opioid overdose and mortality have increased at an alarming rate prompting new public
health initiatives to reduce drug poisoning. One initiative is to expand access to the opioid …

Introduction: Opioid overdose fatality has increased threefold since 1999. As a result,
prescription drug overdose surpassed motor vehicle collision as the leading cause of …

Naloxone is a well-established essential medicine for the treatment of life-threatening
heroin/opioid overdose in emergency medicine. Over two decades, the concept of 'take …

The opioid use and overdose crisis is persistent and dynamic. Opioid overdoses were
initially driven in the 1990s and 2000s by the increasing availability and misuse of …

Over the past 25 years, naloxone has emerged as a critical lifesaving overdose antidote.
Public health advocates and community activists established early methods for naloxone …

Introduction Deaths from opioid overdose can be prevented through administration of the
antagonist naloxone, which has been licensed for injection since the 1970s. To support …

Amidst an ongoing opioid crisis that claimed 47,600 lives in 2017, increasing the availability
of the rescue medication naloxone is a high priority. Naloxone reverses an opioid overdose …