Plant-derived triterpenoids and analogues as antitumor and anti-HIV agents

RY Kuo, K Qian, SL Morris-Natschke, KH Lee - Natural product reports, 2009 - pubs.rsc.org
Covering: January 2006 to December 2008 This article reviews the antitumor and anti-HIV
activities of naturally occurring triterpenoids, including the lupane, ursane, oleanane …

Anti-HIV activity of natural triterpenoids and hemisynthetic derivatives 2004–2009

BK Cassels, M Asencio - Phytochemistry Reviews, 2011 - Springer
The continued advance of HIV-AIDS makes the development of relatively inexpensive, freely
accessible, and mechanistically more diverse antiviral therapies an urgent need. Natural …

Recent advances in antiviral activities of triterpenoids

Y Liu, L Yang, H Wang, Y Xiong - Pharmaceuticals, 2022 - mdpi.com
Triterpenoids, important secondary plant metabolites made up of six isoprene units, are
found widely in higher plants and are studied for their structural variety and wide range of …

Pentacyclic triterpenes of the lupane, oleanane and ursane group as tools in cancer therapy

MN Laszczyk - Planta medica, 2009 - thieme-connect.com
Today cancer treatment is not only a question of eliminating cancer cells by induction of cell
death. New therapeutic strategies also include targeting the tumour microenvironment …

Plant-derived terpenoids and analogues as anti-HIV agents.

IC Sun, Y Kashiwada, SL Morris-Natschke… - Current topics in …, 2003 - europepmc.org
The plant-derived terpenoids and analogues are reviewed with respect to their anti-HIV
activity, structure-activity relationships, and mechanism of action. The active compounds …

Synthesis and anti-HIV activity of lupane and olean-18-ene derivatives. Absolute configuration of 19, 20-epoxylupanes by VCD

F Gutiérrez-Nicolás, B Gordillo-Román… - Journal of natural …, 2012 - ACS Publications
Lupane triterpenoids 2 and 5–12 and oleanene derivatives 13 and 14 were prepared from
lupeol (1), betulin (3), and germanicol (4). They were tested for anti-HIV activity, and some …

Antitumor and antiviral activity of pentacyclic triterpenes

R Paduch, M Kandefer-Szerszen - Mini-Reviews in Organic …, 2014 - ingentaconnect.com
Over the last two decades, extensive research on compounds isolated from fruits,
vegetables, cereals, herbs and medicinal plants has revealed that triterpenoids possess …

Anti-viral triterpenes: a review

P Darshani, S Sen Sarma, AK Srivastava… - Phytochemistry …, 2022 - Springer
Triterpenes are naturally occurring derivatives biosynthesized following the isoprene rule of
Ruzicka. The triterpenes have been reported to possess a wide range of therapeutic …

Natural product triterpenoids and their semi-synthetic derivatives with potential anticancer activity

Y Ren, AD Kinghorn - Planta Medica, 2019 - thieme-connect.com
Triterpenoids are distributed widely in higher plants and are of interest because of their
structural diversity and broad range of bioactivities. In particular, there is a very large …

A review of natural and modified betulinic, ursolic and echinocystic acid derivatives as potential antitumor and anti-HIV agents.

I Baglin, AC Mitaine-Offer, M Nour, K Tan… - Mini reviews in …, 2003 - europepmc.org
The aim of this review is to update current knowledge on the betulinic, ursolic and
echinocystic acids and their natural and semisynthetic analogs, focussing on their cytotoxic …