Cardiovascular effects of estrogens have been shown to be of great clinical importance
treating patients with hormonal replacement therapy or using oral contraceptives. To test …

The calcium antagonistic effect of 17α-estradiol derivatives was investigated in vitro in
human aortic smooth muscle cells. The substances tested were 14α-estradiol, 17α …

Abstract 17β-Estradiol (E 2) plays an important role in Ca 2+ fluxes in several cell types. It
has been proposed that some of its effects are of nongenomic origin E 2 at vascular smooth …

Short-term estrogen administration has been independently proposed to produce arterial
vasodilation by both an indirect mechanism and a direct mechanism (inhibition of calcium …

The effect of estradiol, progesterone, and three progestogens on calcium influx was
investigated in cell cultures of human vessels under resting conditions. Estradiol significantly …

The cardiovascular effects of estrogen are mediated in part by augmenting the function of
endothelial nitric oxide synthase. Endothelial nitric oxide synthase activity is dependent on …

This paper reviews the evidence for calcium-antagonist properties of oestrogen which may
offer long-term protective effects on the cardiovascular system in postmenopausal women …

Epidemiological studies indicate a lower incidence of coronary heart disease in
premenopausal women compared with age-matched men and post-menopausal women …

Estrogen replacement therapy has been found to reduce the incidence of cardio-and
cerebrovascular diseases in postmenopausal women. The mechanisms of this …

We have studied the effects of 17-α-estradiol, a non-estrogenic steroid, on pig coronary
arteries contracted by K+, Ca 2+ or serotonin. Experiments were performed on helicoidal …