Neural network based prediction of conformational free energies-a new route toward coarse-grained simulation models

T Lemke, C Peter - Journal of chemical theory and computation, 2017 - ACS Publications
Coarse-grained (CG) simulation models have become very popular tools to study complex
molecular systems with great computational efficiency on length and time scales that are …

[HTML][HTML] Magic v. 3: An integrated software package for systematic structure-based coarse-graining

A Mirzoev, L Nordenskiöld, A Lyubartsev - Computer Physics …, 2019 - Elsevier
Molecular simulations of many phenomena related to biomolecular systems, soft matter and
nanomaterials require consideration of length scales above 10 nm and time scales longer …

Statistically optimal force aggregation for coarse-graining molecular dynamics

A Krämer, AEP Durumeric, NE Charron… - The Journal of …, 2023 - ACS Publications
Machine-learned coarse-grained (CG) models have the potential for simulating large
molecular complexes beyond what is possible with atomistic molecular dynamics. However …

A review of physics-based coarse-grained potentials for the simulations of protein structure and dynamics

H Shen, Z Xia, G Li, P Ren - Annual Reports in Computational Chemistry, 2012 - Elsevier
By simplifying the atomistic representation of a biomolecular system, coarse-grained (CG)
approach enables the molecular dynamics simulation to reveal the biological processes …

A review of advancements in coarse-grained molecular dynamics simulations

SY Joshi, SA Deshmukh - Molecular Simulation, 2021 - Taylor & Francis
Over the last few years, coarse-grained molecular dynamics has emerged as a way to model
large and complex systems in an efficient and inexpensive manner due to its lowered …

Multiconfigurational coarse-grained molecular dynamics

ME Sharp, FX Vázquez, JW Wagner… - Journal of chemical …, 2019 - ACS Publications
Standard low resolution coarse-grained modeling techniques have difficulty capturing
multiple configurations of protein systems. Here, we present a method for creating accurate …

Coarse-grained protein models and their applications

S Kmiecik, D Gront, M Kolinski, L Wieteska… - Chemical …, 2016 - ACS Publications
The traditional computational modeling of protein structure, dynamics, and interactions
remains difficult for many protein systems. It is mostly due to the size of protein …

[HTML][HTML] Multi-body effects in a coarse-grained protein force field

J Wang, N Charron, B Husic, S Olsson, F Noé… - The Journal of …, 2021 - pubs.aip.org
The use of coarse-grained (CG) models is a popular approach to study complex
biomolecular systems. By reducing the number of degrees of freedom, a CG model can …

Comment on “On using a too large integration time step in molecular dynamics simulations of coarse-grained molecular models” by M. Winger, D. Trzesniak, R. Baron …

SJ Marrink, X Periole, DP Tieleman… - Physical Chemistry …, 2010 - pubs.rsc.org
In a recent study published in this journal, Winger et al. 1 investigate the magnitude of the
time step to integrate the equations of motion in simulations with the coarse-grained …

Transferable and polarizable coarse grained model for proteins─ ProMPT

A Sahoo, PY Lee, S Matysiak - Journal of Chemical Theory and …, 2022 - ACS Publications
The application of classical molecular dynamics (MD) simulations at atomic resolution (fine-
grained level, FG), to most biomolecular processes, remains limited because of the …