Background Nuclear factor erythroid 2-related factor 2 (Nrf2) is a key regulator of
antioxidative stress responses, which are associated with ferroptosis inhibition. Ferroptosis …

Abstract Alzheimer's disease (AD), a neurodegenerative condition, is defined by
neurofibrillary tangles, amyloid plaques, and gradual cognitive decline. Regardless of the …

Abstracts Background Many neurological diseases involve neuroinflammation, during which
overproduction of cytokines by immune cells, especially microglia, can aggregate neuronal …

Simple Summary Sodium butyrate (NaB) is a short-chain fatty acid produced by intestinal
microbial fermentation of dietary fiber. It has been shown to be effective in inhibiting …

Ferroptosis is a newly discovered type of cell death decided by iron-dependent lipid
peroxidation, but its role in glioblastoma cell death remains unclear. Ibuprofen, a …

Background. Ferroptosis is a newly identified form of programmed cell death caused by iron‐
dependent lipid peroxidation. Our study was designed to determine the expression patterns …

Ethnopharmacological relevance Rehmannioside A is derived from Rehmannia glutinosa
Libosch, which is widely used as an important ingredient in diverse traditional Chinese …

Cognitive dysfunction often accompanies diabetes. Both hypoglycemia and hyperglycemia
cause cognitive dysfunctions. However, the underlying pathophysiology remains unclear …

There are few effective and safe neuroprotective agents for the treatment of ischemic stroke
currently. Caffeic acid is a phenolic acid that widely exists in a number of plant species …

Background Berberine (BBR) is a natural alkaloid extracted from the herb Coptis chinensis.
This compound has the ability to penetrate the blood-brain barrier (BBB) and exhibit …