Ethnopharmacological relevance Aconitum species, with a long history of traditional
application, were applied to treat rheumatism, arthritis, stroke, and pain in Chinese medical …

Ferroptosis is implicated in various tumors, including glioblastoma. Artesunate (ART), an anti-
malarial drug, exerted antitumor properties in several cancer types. However, the role of …

Oxidative disruption of dopaminergic neurons is regarded as a crucial pathogenesis in
Parkinson's disease (PD), eventually causing neurodegenerative progression.(-) …

The iron chelator deferoxamine has been shown to inhibit ferroptosis in spinal cord injury.
However, it is unclear whether deferoxamine directly protects neurons from ferroptotic cell …

Oxidative damage including lipid peroxidation is widely reported in Alzheimer's disease
(AD) with the peroxidation of phospholipids in membranes being the driver of ferroptosis, an …

Emerging evidence shows that targeting ferroptosis may be a potential therapeutic strategy
for treating traumatic brain injury (TBI). Hydrogen sulfide (H2S) has been proven to play a …

Alzheimer's disease (AD) is a degenerative disease of the central nervous system that is the
most common type of senile dementia. Ferroptosis is a new type of iron-dependent …

Spinal cord injury (SCI), a devastating neurological impairment, usually imposes a long-term
psychological stress and high socioeconomic burden for the sufferers and their family …

Ferroptosis, a newly discovered iron-dependent cell death, is involved in brain ischemia–
reperfusion injury. Iron scavengers or ferroptosis inhibitors could reduce infarct volume and …

Background Ischemic stroke, a major cause of death and disability worldwide, results from
reduced blood flow to the brain, leading to irreversible neuronal damage. Recent evidence …