Vitamin B12 deficiency in geriatrics

I Bopp-Kistler, B Rüegger-Frey, D Grob, P Six - Praxis, 1999 - europepmc.org
Cobalamin deficiency increases with advancing age. The cut-off point of serum
concentration should be raised, because many elderly people with" normal" serum vitamin …

Effects of oral crystalline cyanocobalamin 1000 μg/d in the treatment of pernicious anemia: an open-label, prospective study in ten patients

E Andrès, NH Loukili, E Noel, F Maloisel… - Current therapeutic …, 2005 - Elsevier
BACKGROUND:: Standard treatment of cobalamin (vitamin B12) deficiency involvesregular
(1000 μg/mo) IM cyanocobalamin administration. It has been suggested that high-dose (> …

12 Cobalamin and folate deficiency in the elderly

JH Matthews - Baillière's clinical haematology, 1995 - Elsevier
Elderly persons are more likely to have low values for serum and erythrocyte folate, and for
serum cobalamin. Many of those with low vitamin levels have biochemical abnormalities …

The syndrome of food-cobalamin malabsorption revisited in a department of internal medicine. A monocentric cohort study of 80 patients

E Andrès, AE Perrin, C Demangeat, JE Kurtz… - European journal of …, 2003 - Elsevier
Background: To date, only case reports or small studies have documented the syndrome of
food-cobalamin malabsorption in specific populations of patients or situations. In this paper …

Randomized trial of the effect of supplementation on the cognitive function of older people with subnormal cobalamin levels

T Kwok, C Tang, J Woo, WK Lai… - … journal of geriatric …, 1998 - Wiley Online Library
Background. Low serum cobalamin levels are often found in apparently normal older
subjects. A major worry of leaving cobalamin deficiency untreated is that it may lead to …

Vitamin B12 (cobalamin)-deficiency in the elderly

E Joosten, W Pelemans, M Hiele… - Nederlands Tijdschrift …, 1990 - europepmc.org
In order to determine the relevance of low vitamin B12 concentration in elderly persons
(greater than 65 years), serum vitamin B12 levels were measured in 292 consecutive …

The frequently low cobalamin levels in dementia usually signify treatable metabolic, neurologic and electrophysiologic abnormalities

R Carmel, PS Gott, CH Waters, K Cairo… - European journal of …, 1995 - Wiley Online Library
Cobalamin levels are frequently low in patients with dementia, but it is unclear if they
represent definable deficiency and what the mechanisms are. Therefore, patients being …

Cobalamin (vitamin B12) malabsorption

E Andres, N Dali-Youcef - Molecular Nutrition, 2020 - Elsevier
Cobalamin (vitamin B 12) deficiency is particularly common whatever the age of the patient,
but may be unrecognized because of its subtle clinical manifestations, although these can …

Cobalamin supplementation improves cognitive and cerebral function in older, cobalamin-deficient persons

DZ van Asselt, JW Pasman, HJ van Lier… - The Journals of …, 2001 - academic.oup.com
Abstract Background. Mild cobalamin (Cbl) deficiency is frequently found in older persons
and is associated with cognitive and cerebral abnormalities. The effects of Cbl …

10 Malabsorption of food cobalamin

R Carmel - Baillière's clinical haematology, 1995 - Elsevier
Food-cobalamin malabsorption is marked by the inability to release cobalamin from food,
which therefore cannot be taken up by intrinsic factor for absorption. The defect is not …