Trials in sleep apnea and stroke: learning from the past to direct future approaches

MI Boulos, L Dharmakulaseelan, DL Brown, RH Swartz - Stroke, 2021 - Am Heart Assoc
Few randomized controlled trials have evaluated the effectiveness of continuous positive
airway pressure (CPAP) in reducing recurrent vascular events and mortality in poststroke …

Obstructive sleep apnea and stroke: the mechanisms, the randomized trials, and the road ahead

S Javaheri, Y Peker, HK Yaggi, CLA Bassetti - Sleep medicine reviews, 2022 - Elsevier
When considered separately from cardiovascular disease, stroke is the third leading cause
of death in the US and is the leading cause of long-term disability in adults. New approaches …

CPAP as treatment of sleep apnea after stroke: a meta-analysis of randomized trials

AK Brill, T Horvath, A Seiler, M Camilo, AG Haynes… - Neurology, 2018 - AAN Enterprises
Objective To perform a systematic review and meta-analysis of randomized controlled trials
(RCTs) examining the effectiveness of continuous positive airway pressure (CPAP) in stroke …

Role of positive airway pressure therapy for obstructive sleep apnea in patients with stroke: a randomized controlled trial

A Gupta, G Shukla, M Afsar, S Poornima… - Journal of Clinical …, 2018 - jcsm.aasm.org
Study Objectives: Obstructive sleep apnea (OSA) is an independent risk factor for stroke.
The objective of this study was to assess the effect of continuous positive airway pressure …

Sleep for stroke management and recovery trial (sleep SMART): rationale and methods

DL Brown, V Durkalski, JS Durmer… - … Journal of Stroke, 2020 - journals.sagepub.com
Rationale Obstructive sleep apnea is common among patients with acute ischemic stroke
and is associated with reduced functional recovery and an increased risk for recurrent …

Sleep disorders and stroke: does treatment of obstructive sleep apnea decrease risk of ischemic stroke?

M Parasram, AZ Segal - Current treatment options in neurology, 2019 - Springer
Purpose of review This review aims to support obstructive sleep apnea (OSA) as a risk factor
for ischemic stroke, review treatment strategies for OSA, provide a comprehensive review of …

Continuous positive airway pressure for treatment of obstructive sleep apnea in stroke survivors: what do we really know?

LM Tomfohr, T Hemmen, L Natarajan, S Ancoli-Israel… - Stroke, 2012 - Am Heart Assoc
Recruitment into randomized studies appeared particularly challenging; investigators
reported screening hundreds of potential participants but enrolling relatively low …

Sleep-disordered breathing and stroke: therapeutic approaches

MC Lipford, JG Park, K Ramar - Current neurology and neuroscience …, 2014 - Springer
The majority of stroke patients have clinically significant obstructive sleep apnea (OSA).
Also, recent evidence demonstrates that OSA serves as an independent risk factor for stroke …

Sleep apnea treatment after stroke (SATS) trial: is it feasible?

DL Brown, RD Chervin, JD Kalbfleisch… - Journal of Stroke and …, 2013 - Elsevier
Sleep apnea affects more than half of patients with acute ischemic stroke and is associated
with poor stroke outcome. This pilot study assessed the feasibility of a randomized, sham …

[HTML][HTML] SAS CARE 2–a randomized study of CPAP in patients with obstructive sleep disordered breathing following ischemic stroke or transient ischemic attack

C Bernasconi, SR Ott, F Fanfulla, S Miano, T Horvath… - Sleep Medicine: X, 2020 - Elsevier
Objective/background The benefit of Continuous Positive Airway Pressure (CPAP) treatment
following ischemic stroke in patients with obstructive sleep-disordered breathing (SDB) is …