Engineering exosomes for cancer therapy
KE Gilligan, RM Dwyer - International journal of molecular sciences, 2017 - mdpi.com
There remains an urgent need for novel therapeutic strategies to treat metastatic cancer,
which results in over 8 million deaths annually worldwide. Following secretion, exosomes …
which results in over 8 million deaths annually worldwide. Following secretion, exosomes …
Exosomes: cell-derived nanoplatforms for the delivery of cancer therapeutics
Exosomes are cell-secreted nanovesicles that naturally contain biomolecular cargoes such
as lipids, proteins, and nucleic acids. Exosomes mediate intercellular communication …
as lipids, proteins, and nucleic acids. Exosomes mediate intercellular communication …
Exosome as a delivery vehicle for cancer therapy
B Moon, S Chang - Cells, 2022 - mdpi.com
Exosomes are small extracellular vesicles that are naturally produced and carry
biomolecules such as proteins, microRNAs, and metabolites. Because of their small size …
biomolecules such as proteins, microRNAs, and metabolites. Because of their small size …
Exploitation of exosomes as nanocarriers for gene-, chemo-, and immune-therapy of cancer
The bottleneck in current vector-based cancer therapy is the targeted and controlled release
of therapeutics in tumors. Exosomes are submicron-sized vesicles that are secreted by all …
of therapeutics in tumors. Exosomes are submicron-sized vesicles that are secreted by all …
Exosomes in cancer development and clinical applications
Exosomes participate in cancer progression and metastasis by transferring bioactive
molecules between cancer and various cells in the local and distant microenvironments …
molecules between cancer and various cells in the local and distant microenvironments …
Recent advances in exosome-based drug delivery for cancer therapy
Simple Summary Exosomes derived from various sources can deliver therapeutic agents
such as small molecule drugs, nucleic acids, and proteins to cancer cells by passive or …
such as small molecule drugs, nucleic acids, and proteins to cancer cells by passive or …
Emerging prospects of exosomes for cancer treatment: from conventional therapy to immunotherapy
Exosomes are a class of extracellular vesicles of around 100 nm in diameter that are
secreted by most cells and contain various bioactive molecules reflecting their cellular origin …
secreted by most cells and contain various bioactive molecules reflecting their cellular origin …
[HTML][HTML] New advances in exosome-based targeted drug delivery systems
D Ferreira, JN Moreira, LR Rodrigues - Critical Reviews in Oncology …, 2022 - Elsevier
In recent years, various drug nano-delivery platforms have emerged to enhance drug
effectiveness in cancer treatment. However, their successful translation to clinics have been …
effectiveness in cancer treatment. However, their successful translation to clinics have been …
[HTML][HTML] A comprehensive review on the composition, biogenesis, purification, and multifunctional role of exosome as delivery vehicles for cancer therapy
J Li, Y Zhang, PY Dong, GM Yang… - Biomedicine & …, 2023 - Elsevier
All forms of life produce nanosized extracellular vesicles called exosomes, which are
enclosed in lipid bilayer membranes. Exosomes engage in cell-to-cell communication and …
enclosed in lipid bilayer membranes. Exosomes engage in cell-to-cell communication and …
Engineering of exosomes to target cancer metastasis
As a nanoscale subset of extracellular vehicles, exosomes represent a new pathway of
intercellular communication by delivering cargos such as proteins and nucleic acids to …
intercellular communication by delivering cargos such as proteins and nucleic acids to …