Alternatives to glucocorticoid monotherapy in the treatment of polymyalgia rheumatica

K Walz, L Elliott, T Pearson - … of the American Association of Nurse …, 2022 - journals.lww.com
Background: Treatment of polymyalgia rheumatica (PMR) can be challenging. The most
efficacious and cost-effective treatment of PMR is some type of glucocorticoid (GC), with …

Treatment of polymyalgia rheumatica: a systematic review

J Hernandez-Rodriguez, MC Cid… - Archives of Internal …, 2009 - jamanetwork.com
Background Polymyalgia rheumatica (PMR) treatment is based on low-dose glucocorticoids.
Glucocorticoid-sparing agents have also been tested. Our objective was to systematically …

Effect of tocilizumab on disease activity in patients with active polymyalgia rheumatica receiving glucocorticoid therapy: a randomized clinical trial

V Devauchelle-Pensec, G Carvajal-Alegria, E Dernis… - Jama, 2022 - jamanetwork.com
Importance Few treatments are available for patients with glucocorticoid-dependent
polymyalgia rheumatica. IL-6 antagonists may reduce disease activity in patients with active …

Efficacy of first-line tocilizumab therapy in early polymyalgia rheumatica: a prospective longitudinal study

V Devauchelle-Pensec, JM Berthelot… - Annals of the …, 2016 - ard.bmj.com
Background Glucocorticoids are the cornerstone treatment of polymyalgia rheumatica (PMR)
but induce adverse events. Objectives To evaluate the efficacy and safety of first-line …

Best practices and uncertainties in the management of PMR

MA González-Gay, J Llorca - Nature Reviews Rheumatology, 2016 - nature.com
Glucocorticoids are the mainstay of treatment for patients with polymyalgia rheumatica
(PMR) and often produce substantial clinical improvements, but treatment can be …

Rapid and sustained response to tocilizumab in patients with polymyalgia rheumatica resistant or intolerant to glucocorticoids: a multicenter open-label study

E Toussirot, A Martin, M Soubrier, S Redeker… - The Journal of …, 2016 - jrheum.org
Polymyalgia rheumatica (PMR) is an inflammatory rheumatic disease affecting people aged
50 years or older. PMR usually improves with glucocorticoids (GC), with rapid resolution of …

Tocilizumab monotherapy for polymyalgia rheumatica: a prospective, single‐center, open‐label study

K Chino, T Kondo, R Sakai, S Saito… - International Journal …, 2019 - Wiley Online Library
Objectives Polymyalgia rheumatica (PMR) is a systemic inflammatory disease in the elderly
of unknown etiology. While glucocorticoids are the mainstay of treatment for PMR, various …

Tocilizumab is effective against polymyalgia rheumatica: experience in 13 intractable cases

K Izumi, H Kuda, M Ushikubo, M Kuwana… - RMD open, 2015 - rmdopen.bmj.com
Polymyalgia rheumatica (PMR) affects older people, and although glucocorticoids are
effective in treating PMR, they frequently result in side effects. Therefore, we conducted a …

POS0926 REAL-WORLD EFFECTIVENESS AND SAFETY OF TOCILIZUMAB IN PATIENTS WITH POLYMYALGIA RHEUMATICA

Y Imai, S Takanashi, Y Kaneko - 2024 - ard.bmj.com
Background: Polymyalgia rheumatica (PMR) responds well to treatment with glucocorticoids,
but high relapse rates during glucocorticoid tapering and adverse events associated with …

Tocilizumab in isolated polymyalgia rheumatica: a systematic literature review

M Akiyama, Y Kaneko, T Takeuchi - Seminars in Arthritis and Rheumatism, 2020 - Elsevier
Objective We investigated the effectiveness of tocilizumab (an anti-interleukin-6 receptor
antibody) in patients with polymyalgia rheumatica (PMR). Methods We performed a …