Dysregulation of c-FLIP (cellular FADD-like IL-1β-converting enzyme inhibitory protein) has
been shown in several diseases including cancer, Alzheimer's disease, and chronic …

Abstract Cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein (c-FLIP) is a
major antiapoptotic protein and an important cytokine and chemotherapy resistance factor …

Cellular FLICE (FADD-like IL-1beta-converting enzyme)-inhibitory protein (c-FLIP) is a major
resistance factor and critical anti-apoptotic regulator that inhibits tumor necrosis factor-alpha …

Death receptors belong to the tumor necrosis factor receptor superfamily and can induce
apoptosis through activation of procaspase-8. The cellular FLICE-inhibitory protein (c-FLIP) …

Cellular FLIP (c-FLIP), also known as FLICE-inhibitory protein, has been identified as an
inhibitor of apoptosis triggered by engagement of death receptors (DRs) such as Fas or …

Cellular-FLICE inhibitory protein (c-FLIP) is a key anti-apoptotic regulator that inhibits cell
death mediated by the death receptors Fas, DR4, DR5, and TNF-R1. Three splice variants of …

Abstract Cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein (c-FLIP) is a
master anti-apoptotic regulator and resistance factor that suppresses tumor necrosis factor-α …

Cellular FLICE-inhibitory protein (c-FLIP) is a catalytically inactive procaspase-8/10
homologue that associates with the signalling complex downstream of death-receptors …

The extrinsic pathway is mediated by death receptors (DRs), including CD95 (APO-1/Fas) or
TRAILR-1/2. Defects in apoptosis regulation lead to cancer and other malignancies. The …

Cellular FLICE-like inhibitory protein (c-FLIP) has been identified as a protease-dead,
procaspase-8-like regulator of death ligand-induced apoptosis, based on observations that c …