Introduction: Somatic mutations accrue in hematopoietic stem cells with age and can lead to
selective clonal expansion, a process termed Clonal Hematopoiesis of Indeterminate …

Background Age-related clonal hematopoiesis of indeterminate potential (CHIP), defined as
clonally expanded leukemogenic sequence variations (particularly in DNMT3A, TET2 …

Background: Clonal hematopoiesis of indeterminate potential (CHIP) was recently identified
as a risk factor for incident heart failure (HF). Whether CHIP is associated selectively with …

Introduction: Clonal hematopoiesis of indeterminate potential (CHIP) is associated with an
increased risk of heart failure (HF) and stroke, particularly HF with preserved ejection …

Introduction: Clonal hematopoiesis of indeterminate potential (CHIP) is an aging-related
accumulation of somatic mutations in hematopoietic stem cells, leading to clonal expansion …

Background: Recent studies have shown that hematopoietic stems cells can undergo clonal
expansion secondary to somatic mutations, termed clonal hematopoiesis of indeterminate …

Introduction: Clonal Hematopoiesis of Indeterminate Potential (CHIP) is a pre-cancerous
age-associated condition characterized by somatic mutations (typically in DNMT3A, TET2 …

Clonal hematopoiesis of indeterminate potential (CHIP) is defined as a clonal outgrowth of
hematopoietic cells with mutations in a restricted set of cancer driver genes in patients …

Background Clonal hematopoiesis of indeterminate potential (CHIP)—the age-related clonal
expansion of blood stem cells with leukemia-associated mutations—is a novel …

Importance Somatic mutations causing clonal expansion of hematopoietic cells (clonal
hematopoiesis of indeterminate potential [CHIP]) are increased with age and associated …