Phenotypic heterogeneity of smooth muscle cells–implications for atherosclerosis

M Coen, ML Bochaton‐Piallat - Atherosclerosis: Molecular and …, 2010 - Wiley Online Library
During atherosclerosis, local secretion of chemokines and growth factors following
endothelial injury, adhesion of platelets, and infiltration of inflammatory cells into the intima …

[引用][C] Immunohistochemical differentiation of arteriosclerotic intimal tissue specimen from primary and restenoses

P Gonschior, A Nerlich, B Mack… - VASA …, 1994 - … -STRASSE 76, CH-3000 BERN 9 …

Differential gene expression in vascular smooth muscle cells in primary atherosclerosis and in stent stenosis in humans

QJ Zhang, M Goddard, C Shanahan… - … , and vascular biology, 2002 - Am Heart Assoc
Objective—We sought to identify differentially expressed genes in human in stent stenosis
(ISS) to provide insights into the mechanism of disease. Methods and Results—Using …

Contractile and cytoskeletal proteins of smooth muscle cells in rat, rabbit and human arteries

AC Thomas, JH Campbell - Tissue and Cell, 2000 - Elsevier
The aim of this study was to determine whether similar populations of smooth muscle cells,
in relation to contractile and cytoskeletal proteins, are present in normal and diseased …

Comprehensive Integration of Multiple Single-Cell Transcriptomic Data Sets Defines Distinct Cell Populations and Their Phenotypic Changes in Murine …

D Sharma, MD Worssam, AJ Pedroza… - … and Vascular Biology, 2024 - Am Heart Assoc
BACKGROUND: The application of single-cell transcriptomic (single-cell RNA sequencing)
analysis to the study of atherosclerosis has provided unique insights into the molecular and …

A combined histochemical and double immunohistochemical labeling protocol for simultaneous evaluation of four cellular markers in restenotic arteries

MR D'Andrea, CJ Rogahn, BP Damiano… - Biotechnic & …, 1999 - Taylor & Francis
We designed an effective quadruple staining protocol that combines histochemistry (HC)
and double-labeling immunohistochemistry (IHC: IHC) to stain simultaneously several …

Quantitative estimation of lipid-laden cells in atherosclerotic lesions of the human aorta

ER Andreeva, AN Orekhov, VN Smirnov - Cells Tissues Organs, 1991 - karger.com
The intima of the adult human aorta consists of three sublayers: a muscular layer lying next
to the media, a median hyperplastic layer and an innermost connective tissue layer …

Phenotype changes in smooth muscle cells of human coronary arteries during aging and during development of atherosclerosis

GK Sukhova, VR Babaev, VN Sirotkin, T Em - Kardiologiia, 1991 - europepmc.org
The ultrastructure and the expression of cytoskeletal and contractile proteins were studied in
the intimal cells of human coronary arteries (CA) taken at autopsy from 38 trauma victims …

Cytoskeletal features of normal andatheromatous human arterial smooth muscle cells

O Kocher, G Gabbiani - Human pathology, 1986 - Elsevier
The distribution of actin, vimentin, desmin, and tropomyosin was studied in the media of the
human aorta and femoral and coronary arteries, as well as in atheromatous plaques from …

Smooth muscle cell phenotypes in atherosclerotic lesions

CM Shanahan, PL Weissberg - Current opinion in lipidology, 1999 - journals.lww.com
Recently, there has been a dramatic change in the way we think about the role of vascular
smooth muscle cells in atherosclerosis, and it is now generally accepted that a dearth of …