Background Proliferation and matrix protein secretion of coronary smooth muscle cells
(SMCs) have been suggested as one of the mechanisms responsible for the development of …

The rupture of an atherosclerotic plaque can have profound consequences, such as
myocardial or cerebrovascular infarction. The complex interactions of vascular smooth …

Objective Here, we identify and quantify leukocytes, macrophages, endothelial cells (ECs),
and vascular smooth muscle cells (VSMCs) with contractile and macrophage-like …

The aim of this study was to reconstruct dynamic biological steps of human atherosclerosis
at different ages of life and, in particular, to clarify the role of the smooth muscle cells (SMCs) …

Phenotypic modulation of smooth muscle cells (SMC) is a key event during the development
of atherosclerotic and restenotic lesions. During this process, the composition of the …

Objective—The present study addresses the question,“Are plaque smooth muscles cells
(SMCs) genetically distinct from medial SMCs as reflected by the ability to maintain a …

Three heart specimens (selected at random) were collected from autopsies done for cases
of accidental deaths. The coronary arteries were perfusion-fixed with 10% neutral buffered …

Smooth muscle cells play an important role in human vascular diseases. Several lines of
evidence demonstrate that circulating smooth muscle precursor cells contribute to intimal …

DISCUSSION Our results, summarized in Table I, show that in experimental intimal
thickening observed in the rat aorta 15 days after balloon-induced endothelial injury, distinct …