Novel targets for parkinsonism-depression comorbidity
Y Tizabi, B Getachew, AB Csoka, KF Manaye… - Progress in Molecular …, 2019 - Elsevier
With the aging population growing and the incidence of neurodegenerative diseases on the
rise, the researchers in the field are yet more urgently challenged to slow and/or reverse the …
rise, the researchers in the field are yet more urgently challenged to slow and/or reverse the …
Neurobiology of depression in Parkinson's disease: Insights into epidemiology, molecular mechanisms and treatment strategies
Parkinson's disease (PD) is characterized mainly by motor dysfunctions due to the
progressive loss of dopaminergic neurons. However, PD patients experience a multitude of …
progressive loss of dopaminergic neurons. However, PD patients experience a multitude of …
[PDF][PDF] Anxiety and Depression: Ignored Neuropsychiatric Aspects of Parkinson's Disease
R Doke, A Bhagwat, K Autade, G Lamkhade… - Eur Chem Bull, 2023 - academia.edu
Millions of people worldwide are afflicted by Parkinson's disease, a kind of progressive brain
condition marked by disturbed movements. Symptoms of PD include disproportionate …
condition marked by disturbed movements. Symptoms of PD include disproportionate …
Converged avenues: depression and Alzheimer's disease–shared pathophysiology and novel therapeutics
S Bajaj, R Mahesh - Molecular Biology Reports, 2024 - Springer
Depression, a highly prevalent disorder affecting over 280 million people worldwide, is
comorbid with many neurological disorders, particularly Alzheimer's disease (AD) …
comorbid with many neurological disorders, particularly Alzheimer's disease (AD) …
Depression in neurodegenerative diseases: Common mechanisms and current treatment options
CPC Galts, LEB Bettio, DC Jewett, CC Yang… - Neuroscience & …, 2019 - Elsevier
Major depressive disorder (MDD) is a highly prevalent psychiatric disorder and a major
cause of disability worldwide. This neurological condition is commonly associated with …
cause of disability worldwide. This neurological condition is commonly associated with …
[HTML][HTML] Emerging pathways to neurodegeneration: Dissecting the critical molecular mechanisms in Alzheimer's disease, Parkinson's disease
SH Tan, V Karri, NWR Tay, KH Chang, HY Ah… - Biomedicine & …, 2019 - Elsevier
Neurodegenerative diseases are usually sporadic in nature and commonly influenced by a
wide range of genetic, life style and environmental factors. A unifying feature of Alzheimer's …
wide range of genetic, life style and environmental factors. A unifying feature of Alzheimer's …
The pathobiological basis of depression in Parkinson disease: challenges and outlooks
KA Jellinger - Journal of neural transmission, 2022 - Springer
Depression, with an estimated prevalence of about 40% is a most common neuropsychiatric
disorder in Parkinson disease (PD), with a negative impact on quality of life, cognitive …
disorder in Parkinson disease (PD), with a negative impact on quality of life, cognitive …
Depression in patients with Parkinson's disease: current understanding of its neurobiology and implications for treatment
S Prange, H Klinger, C Laurencin, T Danaila… - Drugs & Aging, 2022 - Springer
Depression is one of the most frequent and burdensome non-motor symptoms in
Parkinson's disease (PD), across all stages. Even when its severity is mild, PD depression …
Parkinson's disease (PD), across all stages. Even when its severity is mild, PD depression …
Parkinson's disease: Mechanisms, translational models and management strategies
C Raza, R Anjum - Life sciences, 2019 - Elsevier
Parkinson's disease is a progressive neurodegenerative disorder. The classical motor
symptoms include resting tremors, bradykinesia, rigidity and postural instability and are …
symptoms include resting tremors, bradykinesia, rigidity and postural instability and are …
An update on novel and emerging therapeutic targets in Parkinson's disease
R Sawant, A Godad - Metabolic Brain Disease, 2024 - Springer
Parkinson's Disease (PD) remains a significant focus of extensive research aimed at
developing effective therapeutic strategies. Current treatments primarily target symptom …
developing effective therapeutic strategies. Current treatments primarily target symptom …