Polymeric micelles as drug delivery vehicles

Z Ahmad, A Shah, M Siddiq, HB Kraatz - Rsc Advances, 2014 - pubs.rsc.org
Though much progress has been made in drug delivery systems, the design of a suitable
carrier for the delivery of hydrophobic drugs is still a major challenge for researchers. The …

Strategies for improving the payload of small molecular drugs in polymeric micelles

Y Zhang, T Ren, J Gou, L Zhang, X Tao, B Tian… - Journal of Controlled …, 2017 - Elsevier
In the past few years, substantial efforts have been made in the design and preparation of
polymeric micelles as novel drug delivery vehicles. Typically, polymeric micelles possess a …

Overcoming the barriers in micellar drug delivery: loading efficiency, in vivo stability, and micelle–cell interaction

S Kim, Y Shi, JY Kim, K Park… - Expert opinion on drug …, 2010 - Taylor & Francis
Importance of the field: Spontaneously constructed from block copolymers in aqueous
media, the polymer micelle has been extensively studied as a potential carrier of poorly …

Structure and design of polymeric surfactant-based drug delivery systems

VP Torchilin - Journal of controlled release, 2001 - Elsevier
The review concentrates on the use of polymeric micelles as pharmaceutical carriers.
Micellization of biologically active substances is a general phenomenon that increases the …

Polymeric micelles and alternative nanonized delivery vehicles for poorly soluble drugs

Y Lu, K Park - International journal of pharmaceutics, 2013 - Elsevier
Poorly soluble drugs often encounter low bioavailability and erratic absorption patterns in
the clinical setting. Due to the rising number of compounds having solubility issues, finding …

Micellar carriers for the delivery of multiple therapeutic agents

R Thipparaboina, RB Chavan, D Kumar… - Colloids and Surfaces B …, 2015 - Elsevier
Multi-drug therapy is described as a simultaneous or sequential administration of two or
more drugs with similar or different mechanisms of action and is recognized as a more …

New advances in biomedical application of polymeric micelles

A Figueiras, C Domingues, I Jarak, AI Santos, A Parra… - Pharmaceutics, 2022 - mdpi.com
In the last decade, nanomedicine has arisen as an emergent area of medicine, which
studies nanometric systems, namely polymeric micelles (PMs), that increase the solubility …

Polymeric micelles–a new generation of colloidal drug carriers

MC Jones, JC Leroux - European journal of pharmaceutics and …, 1999 - Elsevier
Polymeric micelles have recently emerged as a novel promising colloidal carrier for the
targeting of poorly water soluble and amphiphilic drugs. Polymeric micelles are considerably …

Polymeric micelles as drug carriers: their lights and shadows

M Yokoyama - Journal of drug targeting, 2014 - Taylor & Francis
In this review, polymeric micelles as drug-targeting carriers are concisely explained. In the
first introduction part, I describe a brief history of polymer micelle's research for drug …

Polymeric micelles for drug targeting

A Mahmud, XB Xiong, HM Aliabadi… - Journal of drug …, 2007 - Taylor & Francis
Polymeric micelles are nano-delivery systems formed through self-assembly of amphiphilic
block copolymers in an aqueous environment. The nanoscopic dimension, stealth properties …