[HTML][HTML] Occurrence of a paroxysmal nocturnal hemoglobinuria clone in an essential thrombocythemia: a link between PIGV and MPL

A Knaus, F Vergez, C Garcia, H Engels… - …, 2022 - ncbi.nlm.nih.gov
Figure 1. Follow-up over time of biochemical (LDH, creatininemia, proteinuria [urinary
protein to creatinine ratio, uPCr], soluble urokinase-type plasminogen receptor [uPAR]) and …

Expansion of paroxysmal nocturnal hemoglobinuria clones in MPLW515L mutation harboring primary myelofibrosis

K Kirito - Annals of Hematology, 2020 - Springer
Dear Editor, Paroxysmal nocturnal hemoglobinuria (PNH) is a hemolytic disease caused by
the expansion of hematopoietic cells with an acquired somatic mutation in the PIG-A gene …

Paroxysmal nocturnal hemoglobinuria assessment by flow cytometric analysis

M Keeney, A Illingworth… - Clinics in laboratory …, 2017 - labmed.theclinics.com
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare acquired hematopoietic stem cell
disorder resulting from the somatic mutation of the X-linked phosphatidylinositolglycan …

A cascade of thromboembolic processes in a patient with paroxysmal nocturnal haemoglobinuria terminated by treatment with eculizumab

REG Schutgens… - Thrombosis and …, 2011 - thieme-connect.com
Paroxysmal nocturnal haemoglobinuria (PNH) is a clonal acquired haematopoietic stem cell
disorder characterised by a mutation in the PIG-A gene, resulting in deficiency of …

[HTML][HTML] Significant hemolysis is not required for thrombosis in paroxysmal nocturnal hemoglobinuria

M Griffin, P Hillmen, T Munir, S Richards, L Arnold… - …, 2019 - ncbi.nlm.nih.gov
Paroxysmal nocturnal hemoglobinuria (PNH), a rare hematological condition, presents with
hemolytic or thrombotic symptoms. PNH stem cells arise due to somatic mutations in the …

Clinical significance of PNH clones in 3085 patients with cytopenia: a large single-center experience

B Fattizzo, A Dunlop, R Ireland, S Kassam, D Yallop… - HEMASPHERE, 2018 - air.unimi.it
Background Paroxysmal nocturnal hemoglobinuria (PNH) is a rare clonal disorder due to
GPI anchored proteins deficiency on blood cells surface, resulting in complement activation …

[PDF][PDF] Cardiopulmonary bypass in a patient with classic paroxysmal nocturnal hemoglobinuria during treatment with eculizumab

STA van Bijnen, H Vermeer… - European Journal of …, 2011 - repository.ubn.ru.nl
Paroxysmal Nocturnal Hemoglobinuria (PNH) is a rare disease characterized by chronic
intravascular hemolysis and a highly increased risk for thrombosis. A mutation of the …

Paroxysmal nocturnal hemoglobinuria: Test to monitor the action of eculizumab treatment

M Arcavi, F Ceballo, MB Caracciolo… - … Journal of Laboratory …, 2020 - Wiley Online Library
Introduction Paroxysmal nocturnal hemoglobinuria (PNH) is caused by a somatic mutation in
the PIG‐A gene, which encodes for glycosylphosphatidylinositol, a phospholipid membrane …

[PDF][PDF] Possible high risk of thrombotic events in patients with paroxysmal nocturnal haemoglobinuria after discontinuation of eculizumab

ST Van Bijnen, RS van Rijn, S Koljenovic… - Br J …, 2012 - repository.ubn.ru.nl
Paroxysmal Nocturnal Hemoglobinuria (PNH) is characterized by chronic intravascular
hemolysis and a high risk of thrombosis, on a background of variable pancytopenia. The …

[HTML][HTML] The spectrum of paroxysmal nocturnal hemoglobinuria clinical presentation in a Brazilian single referral center

BGP Pires da Silva, NP Fonseca, LFB Catto… - Annals of …, 2022 - Springer
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare hematological disorder caused by the
expansion of a hematopoietic clone harboring a somatic genetic variant in the PIG-A gene …