Laboratory aids for the diagnosis of acute rheumatic fever include the determination of
antibodies to streptococcal extracellular products, the elevation of which is a confirmatory …

The presumable stimulus for this progressive increase in antistreptolysin is the continuous re-
lease of streptolysin into the tissues of the patient. If the release of streptolysin should occur …

T HE INDISTINCT bounidaries of the eliiiical picture of rheumatic fever and the lack of a
speeific aiagnostic test have led to the formulation of an arbitrary list of criteria for the …

RHEUMATIC fever is now generally accepted to be a complication of infection with Group A
streptococci. The pathogenesis of this complication is as yet unknown. Moreover, the …

Although the incidence of rheumatic fever has declined significantly over the last decade,
testing for antibodies to streptococcal extracellular enzymes maintains an important role in …

Introduction. The technical procedures used in this study have been described, the
specificity of the tests has been discussed, and the incidence of three types of antibodies to …

Recent advances in laboratory and clinical investigation have shown the constant
association of acute rheumatic fever with Group A beta-hemolytic streptococcal infections …

The clinical course of rheumatic fever in relation to the factor of streptococcal infection was
studied in 580 patients. A high initial titer of either antistreptolysin O, antistreptokinase or …

N order to evaluate the evidence which indicates a close relationship between rheumatic
fever and infections with hemolvtic streptococci, it is advisable to have a clear picture of our …

A series of 3,114 skin tests was performed during the summer of 1928 in European clinics
on 594 individuals among whom were 42 active and 146 inactive or" cured" cases of …