A major part of the human Y chromosome consists of palindromes with multiple copies of
genes primarily expressed in testis, many of which have been claimed to affect male fertility …

Because of its highly repetitive nature, the human male-specific Y chromosome remains
understudied. It is important to investigate variation on the Y chromosome to understand its …

In man, infertility is associated with microdeletions of specific regions of the long arm of the Y
chromosome. This indicates that factors encoded by the Y chromosome are necessary for …

Mosaic chromosomal alterations (mCAs) are classified as mosaic deletions (loss), copy-
neutral loss of heterozygosity (CN-LOH), and duplications (gain), attracting special attention …

Mosaic chromosomal alterations (mCAs) are common in cancers and can arise decades
before diagnosis. A quantitative understanding of the rate at which these events occur, and …

Y chromosome deletions arise frequently in human populations, where they cause sex
reversal and Turner syndrome and predispose individuals to infertility and germ cell cancer …

Male and female differ genetically by their respective sex chromosome composition, that is,
XY as male and XX as female. Although both X and Y chromosomes evolved from the same …

Mosaic chromosomal alterations (mCAs) are frequently observed in cancer cells and are
regarded as one of the common features of cancers. Strikingly, accumulating studies …

Background Life expectancy is 10–20 years lower in patients with schizophrenia than in the
general population. In addition, men with schizophrenia have an earlier age at onset, more …

Objective: The male-specific region of the Y chromosome (MSY) remains one of the most
unexplored regions of the genome. We sought to examine how the genetic variants of the …