Molecular and clinical prognostic biomarkers of COVID-19 severity and persistence

G Papadopoulou, E Manoloudi, N Repousi, L Skoura… - Pathogens, 2022 - mdpi.com
The coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory
syndrome coronavirus-2 (SARS-CoV-2), poses several challenges to clinicians, due to its …

Biomarker profiles associated with COVID-19 severity and mortality

S Sánchez-Díez, C Gómez-Ollés, MJ Cruz… - Current Issues in …, 2023 - mdpi.com
Introduction: The aim of this study was to analyze biomarkers that might predict the severity
and progression of the SARS-CoV-2 infection, both in the acute phase and after recovery …

Identification and validation of predictive factors for progression to severe COVID-19 pneumonia by proteomics

B Di, H Jia, OJ Luo, F Lin, K Li, Y Zhang… - Signal transduction and …, 2020 - nature.com
Recent study showed that around 80% of coronavirus disease-19 (COVID-19) patients are
moderate cases who will recover with or without conventional treatment, while the remaining …

Redefining COVID-19 severity and prognosis: the role of clinical and immunobiotypes

J Torres-Ruiz, A Perez-Fragoso… - Frontiers in …, 2021 - frontiersin.org
Background Most of the explanatory and prognostic models of COVID-19 lack of a
comprehensive assessment of the wide COVID-19 spectrum of abnormalities. The aim of …

Machine learning assisted prediction of prognostic biomarkers associated with COVID-19, using clinical and proteomics data

R Sardar, A Sharma, D Gupta - Frontiers in genetics, 2021 - frontiersin.org
With the availability of COVID-19-related clinical data, healthcare researchers can now
explore the potential of computational technologies such as artificial intelligence (AI) and …

In silico transcriptional analysis of asymptomatic and severe COVID-19 patients reveals the susceptibility of severe patients to other comorbidities and non-viral …

P Sen, H Kaur - Human Gene, 2023 - Elsevier
COVID-19 is a severe respiratory disease caused by SARS-CoV-2, a novel human
coronavirus. Patients infected with SARS-CoV-2 exhibit heterogeneous symptoms that pose …

Potential biomarkers for the early prediction of SARS-COV-2 disease outcome

V Mariappan, PS Manoharan, R Pajanivel… - Microbial …, 2021 - Elsevier
The current pandemic due to the fast spreading of SARS-CoV-2 infection has caused severe
impairment in health, social, economic, scientific, and medical sectors across the globe …

Transcriptomic studies revealed pathophysiological impact of COVID-19 to predominant health conditions

Z Nain, SK Barman, MM Sheam, SB Syed… - Briefings in …, 2021 - academic.oup.com
Despite the association of prevalent health conditions with coronavirus disease 2019
(COVID-19) severity, the disease-modifying biomolecules and their pathogenetic …

Clinical predictors of COVID-19 severity and mortality: a perspective

J Sharma, R Rajput, M Bhatia, P Arora… - Frontiers in Cellular and …, 2021 - frontiersin.org
The COVID-19 pandemic has caused huge socio-economic losses and continues to threat
humans worldwide. With more than 4.5 million deaths and more than 221 million confirmed …

[HTML][HTML] Human‐host transcriptomic analysis reveals unique early innate immune responses in different sub‐phenotypes of COVID‐19

R Maurya, U Shamim, P Chattopadhyay… - Clinical and …, 2022 - ncbi.nlm.nih.gov
Dear Editor, The diverse clinical manifestations of COVID-19 are substantially modulated by
host immune responses, emphasising the need for investigating the initial Transcriptional …