Changes in Ca2+ signals within the myometrium have important functional consequences,
as they determine contractility. We show that the basic phasic nature of uterine contractions …

The regulation of myometrial contraction is of paramount importance for the maintenance of
pregnancy and for parturition. Understanding this regulation involves delineating the …

Myometrial contractility is a complex and dynamic physiological process that changes
substantially during pregnancy and culminates in childbirth. Uterine contractions are …

If we are to develop new strategies for the treatment and management of preterm and
dysfunctional term labour, it is imperative that we improve current understanding of the …

This article reviews the contribution of ion channels to membrane potential, the ion channels
expressed in myometrium, and the effect of ion channel activity on the control of myometrial …

A rise in intracellular calcium (Ca 2+) is central to control of contractile activity in myometrium
(see first and second articles in this issue). In nervous tissue, sodium (Na § entry into tissue …

Cellular mechanisms regulating myometrial intracellular free calcium (Ca 2+ i) are
addressed in this review, with emphasis on G-protein-coupled receptor pathways. An …

BACKGROUND Uterine contractile activity plays an important role in many and varied
reproductive functions including sperm and embryo transport, implantation, menstruation …

In this review we discuss our current understanding of the cellular basis of uterine
contractility, highlighting those areas requiring further study. It is clear that the basic …

In this review, we give a state‐of‐the‐art account of uterine contractility, focussing on
excitation–contraction (electro‐mechanical) coupling (ECC). This will show how …