BACKGROUND AND PURPOSE: Prior MR imaging studies, primarily at 1.5 T, established
hippocampal atrophy as a biomarker for Alzheimer disease. 3T MR imaging offers a higher …

In Alzheimer's disease (AD), the hippocampus is an early site of tau pathology and
neurodegeneration. Histological studies have shown that lesions are not uniformly …

Hippocampal atrophy rate—measured using automated techniques applied to structural MRI
scans—is considered a sensitive marker of disease progression in Alzheimer's disease …

We applied the hippocampal radial atrophy mapping technique to the baseline and follow‐
up magnetic resonance image data of 169 amnestic mild cognitive impairment (MCI) …

As one of the earliest structures to degenerate in Alzheimer's disease (AD), the
hippocampus is the target of many studies of factors that influence rates of brain …

Histological studies have suggested differing involvement of the hippocampal subfields in
ageing and in Alzheimer's disease. The aim of this study was to assess in vivo local …

BACKGROUND AND PURPOSE: Hippocampus volumetry is a useful surrogate marker for
the diagnosis of Alzheimer disease, but it seems insufficiently sensitive for the aMCI stage …

Atrophic changes of the hippocampus are typically regarded as an early sign of Alzheimer's
dementia (AD). Using the radial distance atrophy mapping approach, we compared the …

Hippocampal atrophy, amyloid plaques, and neurofibrillary tangles are established
pathologic markers of Alzheimer's disease. We analyzed the temporal lobes of 9 Alzheimer's …

The measurement of hippocampal volumes using MRI is a useful in-vivo biomarker for
detection and monitoring of early Alzheimer's disease (AD), including during the amnestic …