The clinical observation that hypertension is more common in males and postmenopausal
women than in premenopausal women suggests vascular protective effects of female sex …

We investigated whether putative vascular protection against hypertension in females
reflects differences in the Ca2+ mobilization mechanisms of vasoconstriction depending on …

The hypothesis that vascular protection in females and its absence in males reflects gender
differences in [Ca2+] i and Ca2+ mobilization mechanisms of vascular smooth muscle …

Abstract 17β-Estradiol induces vasodilation in vitro and in vivo, which has been suggested
to contribute to the cardiovascular protection by this ovarian steroid hormone. However, the …

Bolus intravenous injections of 100 micrograms/kg 17 beta-estradiol significantly decreased
the pressor responses to norepinephrine (NE; 0.3 microgram/kg) at the fourth, fifth, and sixth …

To elucidate the mechanisms of estrogens-induced relaxation effects on vascular smooth
muscle cells, the effects of estrogens and the related hormones were examined in cultured …

The clinical observation that coronary artery disease is more common in men and
postmenopausal women than in premenopausal women has suggested cardioprotective …

Acute estrogen administration relaxes vascular smooth muscle by decreasing intracellular
Ca2+ concentration ([Ca2+] i). In the present study, we examined the hypothesis that this …

The greater incidence of hypertension and coronary artery disease in men and
postmenopausal women compared with premenopausal women has been related, in part, to …

In isolated aortae of the male rat [Mg2+] o withdrawal and concomitant reduction in [Na+] o
(to 84 mm) induced significant increases of basal tone, but, surprisingly, this did not occur in …