Do similar neural systems subserve aggressive and sexual behaviour in male rats? Insights from c-Fos and pharmacological studies

JG Veening, LM Coolen, TR de Jong… - European journal of …, 2005 - Elsevier
It is a common belief that male aggressive and sexual behaviour share many of the
underlying neurobiological, neurological, pharmacological and neuroendocrine …

An effect of serotonergic stimulation on learning rates for rewards apparent after long intertrial intervals

K Iigaya, MS Fonseca, M Murakami, ZF Mainen… - Nature …, 2018 - nature.com
Serotonin has widespread, but computationally obscure, modulatory effects on learning and
cognition. Here, we studied the impact of optogenetic stimulation of dorsal raphe serotonin …

Hallucinogens recruit specific cortical 5-HT2A receptor-mediated signaling pathways to affect behavior

J González-Maeso, NV Weisstaub, M Zhou, P Chan… - Neuron, 2007 - cell.com
Hallucinogens, including mescaline, psilocybin, and lysergic acid diethylamide (LSD),
profoundly affect perception, cognition, and mood. All known drugs of this class are 5-HT 2A …

Serotonin depletion amplifies distinct human social emotions as a function of individual differences in personality

JW Kanen, FE Arntz, R Yellowlees, RN Cardinal… - Translational …, 2021 - nature.com
Serotonin is involved in a wide range of mental capacities essential for navigating the social
world, including emotion and impulse control. Much recent work on serotonin and social …

Chronic fluoxetine bidirectionally modulates potentiating effects of serotonin on the hippocampal mossy fiber synaptic transmission

K Kobayashi, Y Ikeda, E Haneda… - Journal of …, 2008 - Soc Neuroscience
Selective serotonin reuptake inhibitors (SSRIs) have been used to treat various psychiatric
disorders. Although the cellular mechanisms underlying amelioration of particular symptoms …

Central 5-HT receptors and their function; present and future

T Sharp, NM Barnes - Neuropharmacology, 2020 - Elsevier
Since our review of central 5-HT receptors and their function twenty years ago, no new 5-HT
receptor has been discovered and there is little evidence that this situation will change in the …

Brain 5-HT deficiency increases stress vulnerability and impairs antidepressant responses following psychosocial stress

BD Sachs, JR Ni, MG Caron - Proceedings of the National …, 2015 - National Acad Sciences
Brain serotonin (5-HT) deficiency and exposure to psychosocial stress have both been
implicated in the etiology of depression and anxiety disorders, but whether 5-HT deficiency …

Role of the 5-HT2A receptor in self-and other-initiated social interaction in lysergic acid diethylamide-induced states: a pharmacological fMRI study

KH Preller, L Schilbach, T Pokorny… - Journal of …, 2018 - Soc Neuroscience
Distortions of self-experience are critical symptoms of psychiatric disorders and have
detrimental effects on social interactions. In light of the immense need for improved and …

Relevance of dorsal raphe nucleus firing in serotonin 5-HT2C receptor blockade-induced augmentation of SSRIs effects

F Sotty, JHA Folgering, LT Brennum, S Hogg, A Mørk… - …, 2009 - Elsevier
Selective serotonin reuptake inhibitors are the most widely prescribed antidepressant drugs.
However, they exhibit a slow onset of action, putatively due to the initial decrease in …

A role for the 5-HT1A, 5-HT4 and 5-HT6 receptors in learning and memory

MV King, CA Marsden, KCF Fone - Trends in pharmacological sciences, 2008 - cell.com
The serotonergic system is implicated in the neurobiological control of learning and memory,
both in healthy individuals and pathological disorders, although the underlying mechanisms …