Chaihu-Shugan-San (CSS) is a traditional botanical drug formula often prescribed to treat
depression in oriental countries, but its pharmacotherapeutic mechanism remains unknown …

Accumulating evidence highlights the link between gut microbiota and depression. As an
antidepressant herbal drug in clinic, Chaihu-Shu-Gan-San (CSGS) has also been used in …

Ethnopharmacological relevance Xiaoyaosan (XYS), a representative and classic
prescription in traditional Chinese medicines (TCMs), has been used for thousands of years …

Abstract Ethnopharmacological relevance Kai-Xin-San (KXS) has been prescribed by TCM
doctors for treating psychiatric diseases with the core symptoms of anhedonia, amnesia, and …

The number of depressed people has increased worldwide. Dysfunction of the gut
microbiota has been closely related to depression. The mechanism by which jasmine tea …

Gut microbiota has emerged as a crucial target of gut-brain axis to influence depression. Zhi-
Zi-Chi decoctions (ZZCD), as a classic oral formula in clinic, is widely applied in depression …

Shugan Jieyu Capsule (SG) has been widely used in China to treat mild to moderate
depression. Hypericum perforatum L.(St John's Wort, SJW) is the main ingredient of SG and …

Background: Recent studies suggest that gut microbiota was associated with the
bidirectional gut-brain axis which could modulate neuropsychological functions of the …

Gut microbiota dysbiosis is a recognized contributing factor to many noncommunicable
diseases, but more evidence is still needed to illustrate its causative impact on mental and …

Abstract Background Chaihu-Shugan-San (CSS, named Shihosogansan in Korean), a
Chinese traditional medicine, is frequently used to treat anxiety and depression. Psychiatric …