Endogenous polyamines mediate acute metabolic effects and cardiac hypertrophy
associated to β-adrenoceptor stimulation. The aim of this study is to characterize the role of …

Ornithine decarboxylase(ODC) is a marker of tissue growth and development and, because
sympathetic stimulation of beta adrenergic receptors acutely increases ODC in the adult rat …

Stimulation of ornithine decarboxylase (ODC) activity was examined in cultured heart cells
from neonatal rats. Fetal bovine serum had a concentration-dependent effect on ODC …

Polyamines contribute to several physiological and pathological processes, including
cardiac hypertrophy in experimental animals. This involves an increase in ornithine …

To evaluate the role of polyamine biosynthesis in myocardial growth, the activity of ornithine
decarboxylase (ODC) and the levels of the polyamines, spermidine, spermine, and …

Ornithine decarboxylase (ODC) is the first and rate-controlling enzyme in the synthesis of
polyamines, which are essential for normal cell growth. We have previously demonstrated …

Myocardial phosphorylase alpha activity responds to stimulation by catecholamines and
thyroid hormone. In hyperthyroidism this enzyme is supersensitive to beta-adrenergic …

Background/Aim: Polyamines (putrescine, spermidine and spermine) play an essential role
in cell growth, differentiation and apoptosis. Hypertrophy is accompanied by an increase in …

Objective: Ornithine decarboxylase (ODC) is an initial rate-limiting enzyme in the synthesis
of polyamines (putrescine, spermidine, and spermine) that play a role in cell growth and …

Inhibition of cardiac ornithine decarboxylase (ODC) by α-difluoromethylornithine (DFMO) did
not prevent normal cardiac growth in mature rats but attenuated isoproterenol-induced …