Glibenclamide-loaded self-nanoemulsifying drug delivery system: development and characterization

SK Singh, PR Prasad Verma… - Drug development and …, 2010 - Taylor & Francis
Objective: To develop and characterize self-nanoemulsifying drug delivery system
(SNEDDS) of the poorly water-soluble drug, glibenclamide (GBD). Methods: Solubility of …

Self-nanoemulsifying drug delivery system of glimepiride: design, development, and optimization

SR Shah, RH Parikh, JR Chavda… - PDA Journal of …, 2013 - journal.pda.org
The objective of the present investigation was to develop and characterize the self-
nanoemulsifying drug delivery system (SNEDDS) of glimepiride, a poorly soluble drug …

[HTML][HTML] Design, optimization and evaluation of glipizide solid self-nanoemulsifying drug delivery for enhanced solubility and dissolution

RN Dash, H Mohammed, T Humaira… - Saudi Pharmaceutical …, 2015 - Elsevier
A solid self-nanoemulsifying drug-delivery system (solid SNEDDS) has been explored to
improve the solubility and dissolution profile of glipizide. SNEDDS preconcentrate was …

Formulation of spray congealed microparticles with self-emulsifying ability for enhanced glibenclamide dissolution performance

B Albertini, MD Sabatino, C Melegari… - Journal of …, 2015 - Taylor & Francis
Purpose: To develop a novel preparation approach of solid Self-Emulsifying Drug Delivery
System (s-SEDDS) based on spray congealing as potential drug delivery technology for …

Improved anti-diabetic activity of glibenclamide using oral self nano emulsifying powder

A Bari, N Chella, K Sanka, NR Shastri… - Journal of …, 2015 - Taylor & Francis
The objective of the present study was to improve solubility, dissolution rate and therapeutic
efficacy of a BCS Class II drug, glibenclamide by using oral self nano emulsifying powder …

Self nanoemulsifying drug delivery system-a novalapproach for improving bioavailability

S Gautam, AK Singh - Journal of Drug Delivery and Therapeutics, 2014 - jddtonline.info
The primary object of self-nanoemulsifying drug delivery system (SNEDDS) is to enhance
the oral bioavailability of poorly water soluble drugs. The major problem in oral formulations …

In vitro and in vivo evaluation of self-nanoemulsifying drug delivery systems of cilostazol for oral and parenteral administration

DB Mahmoud, MH Shukr, ER Bendas - International journal of …, 2014 - Elsevier
The current investigation was aimed to improve the solubility of poorly soluble drug,
cilostazol (CLZ). Self-nanoemulsifying drug delivery system (SNEDDS) composed of oil …

Polymeric solid self-nanoemulsifying drug delivery system of glibenclamide using coffee husk as a low cost biosorbent

F Shakeel, N Haq, FK Alanazi, IA Alsarra - Powder technology, 2014 - Elsevier
Surface adsorbed chitosan-loaded solid self-nanoemulsifying drug delivery system (S-
SNEDDS) of glibenclamide (GBN) was developed. Low cost coffee husk was investigated as …

[PDF][PDF] Formulation and in-vitro characterization of selfnanoemulsifying drug delivery system of cinnarizine

PK Suresh, S Sharma - drugs, 2011 - academia.edu
The oral drug delivery is fraught with low and erratic bioavailability owing to enzymatic
degradation of drug, poor permeability, poor solubility and dissolution, intestinal efflux and …

Design and evaluation of self-nanoemulsifying pellets of repaglinide

NS Desai, MS Nagarsenker - AAPS PharmSciTech, 2013 - Springer
The aim of study was to develop self-nanoemulsifying pellets (SNEP) for oral delivery of
poorly water soluble drug, repaglinide (RPG). Solubility of RPG in oily phases and …