[HTML][HTML] The role of hippocampal spatial representations in contextualization and generalization of fear
LD de Voogd, YPJ Murray, RM Barte, A van der Heide… - Neuroimage, 2020 - Elsevier
Using contextual information to predict aversive events is a critical ability that protects from
generalizing fear responses to safe contexts. Animal models have demonstrated the …
generalizing fear responses to safe contexts. Animal models have demonstrated the …
[HTML][HTML] The complex nature of hippocampal-striatal interactions in spatial navigation
Decades of research have established the importance of the hippocampus for episodic and
spatial memory. In spatial navigation tasks, the role of the hippocampus has been classically …
spatial memory. In spatial navigation tasks, the role of the hippocampus has been classically …
Distributed and multifaceted effects of threat and safety
In the present fMRI study, we examined how anxious apprehension is processed in the
human brain. A central goal of the study was to test the prediction that a subset of brain …
human brain. A central goal of the study was to test the prediction that a subset of brain …
Exposure to a fearful context during periods of memory plasticity impairs extinction via hyperactivation of frontal-amygdalar circuits
JM Stafford, DAK Maughan, EC Ilioi… - Learning & …, 2013 - learnmem.cshlp.org
An issue of increasing theoretical and translational importance is to understand the
conditions under which learned fear can be suppressed, or even eliminated. Basic research …
conditions under which learned fear can be suppressed, or even eliminated. Basic research …
Parallel striatal and hippocampal systems for landmarks and boundaries in spatial memory
How the memory systems centered on the hippocampus and dorsal striatum interact to
support behavior remains controversial. We used functional MRI while people learned the …
support behavior remains controversial. We used functional MRI while people learned the …
Ventral hippocampus interacts with prelimbic cortex during inhibition of threat response via learned safety in both mice and humans
Heightened fear and inefficient safety learning are key features of fear and anxiety disorders.
Evidence-based interventions for anxiety disorders, such as cognitive behavioral therapy …
Evidence-based interventions for anxiety disorders, such as cognitive behavioral therapy …
Medial prefrontal pathways for the contextual regulation of extinguished fear in humans
The maintenance of anxiety disorders is thought to depend, in part, on deficits in extinction
memory, possibly due to reduced contextual control of extinction that leads to fear renewal …
memory, possibly due to reduced contextual control of extinction that leads to fear renewal …
Long-term stabilization of place cell remapping produced by a fearful experience
Fear is an emotional response to danger that is highly conserved throughout evolution
because it is critical for survival. Accordingly, episodic memory for fearful locations is widely …
because it is critical for survival. Accordingly, episodic memory for fearful locations is widely …
Selective roles for hippocampal, prefrontal cortical, and ventral striatal circuits in radial-arm maze tasks with or without a delay
SB Floresco, JK Seamans, AG Phillips - Journal of Neuroscience, 1997 - Soc Neuroscience
The hippocampus, the prefrontal cortex, and the ventral striatum form interconnected neural
circuits that may underlie aspects of spatial cognition and memory. In the present series of …
circuits that may underlie aspects of spatial cognition and memory. In the present series of …
[PDF][PDF] Hippocampal attractor dynamics predict memory-based decision making
B Steemers, A Vicente-Grabovetsky, C Barry… - Current Biology, 2016 - cell.com
Memories are thought to be retrieved by attractor dynamics if a given input is sufficiently
similar to a stored attractor state [1–5]. The hippocampus, a region crucial for spatial …
similar to a stored attractor state [1–5]. The hippocampus, a region crucial for spatial …