Oxidative stress and chronic inflammation are important features in the pathogenesis of
chronic obstructive pulmonary disease (COPD). Oxidative stress has important …

Oxidative stress is an important feature in the pathogenesis of COPD. Targeting oxidative
stress with antioxidants or boosting the endogenous levels of antioxidants is likely to be …

Increased oxidative stress occurs in the lungs and systemically in COPD, which plays a role
in many of the pathogenic mechanisms in COPD. Hence, targeting local lung and systemic …

Cigarette/tobacco smoke/biomass fuel-induced oxidative and aldehyde/carbonyl stress are
intimately associated with the progression and exacerbation of chronic obstructive …

There is a marked increase in oxidative stress in the lungs of patients with COPD, as
measured by increased exhaled 8-isoprostane, ethane, and hydrogen peroxide in the …

Chronic obstructive pulmonary disease (COPD) is a leading cause of mortality and morbidity
globally, and its development is mainly associated with tobacco/biomass smoke-induced …

Smoking is the main etiologic factor in chronic obstructive pulmonary disease (COPD).
Cigarette smoke produces an enormous oxidant burden on the lungs, which is exacerbated …

Oxidative stress is now recognized as a major predisposing factor in the pathogenesis of
COPD. Existing therapies for COPD are ineffective at halting disease progression, with …

There is considerable evidence that an increased oxidative burden occurs in the lungs of
patients with chronic obstructive pulmonary disease (COPD) and this results in an …

Oxidative stress is a major driving mechanism in the pathogenesis of COPD. There is
increased oxidative stress in the lungs of COPD patients due to exogenous oxidants in …