Pharmacological activities, mechanisms of action, and safety of salidroside in the central nervous system

Z Zhong, J Han, J Zhang, Q Xiao, J Hu… - Drug design …, 2018 - Taylor & Francis
The primary objective of this review article was to summarize comprehensive information
related to the neuropharmacological activity, mechanisms of action, toxicity, and safety of …

[HTML][HTML] Pharmacological effects of salidroside on central nervous system diseases

M Jin, C Wang, Y Xu, Z Zhang, X Wu, R Ye… - Biomedicine & …, 2022 - Elsevier
Salidroside (SAL) is a phenylpropanoid glycoside monomer extracted from Rhodiola at high
altitudes. It has been proven to have protective effects on myocardial injury, liver cancer …

Salidroside: A review of its recent advances in synthetic pathways and pharmacological properties

X Zhang, L Xie, J Long, Q Xie, Y Zheng, K Liu… - Chemico-Biological …, 2021 - Elsevier
Salidroside has been identified as one of the most potent compounds isolated from various
Rhodiola plants, which have been used for a long time as adaptogens in traditional Chinese …

[HTML][HTML] Salidroside as a potential neuroprotective agent for ischemic stroke: a review of sources, pharmacokinetics, mechanism and safety

F Fan, L Yang, R Li, X Zou, N Li, X Meng… - Biomedicine & …, 2020 - Elsevier
Salidroside (Sal) is a bioactive extract principally from traditional herbal medicine such as
Rhodiola rosea L., which has been commonly used for hundreds of years in Asia countries …

Development and validation of a liquid chromatographic/electrospray ionization mass spectrometric method for the determination of salidroside in rat plasma …

S Yu, L Liu, T Wen, Y Liu, D Wang, Y He… - … of Chromatography B, 2008 - Elsevier
A sensitive and specific liquid chromatography–electrospray ionization-mass spectrometry
(LC–ESI-MS) method has been developed and validated for the identification and …

Salidroside-can it be a multifunctional drug?

SKJ Magani, SD Mupparthi, BP Gollapalli… - Current Drug …, 2020 - ingentaconnect.com
Background: Salidroside is a glucoside of tyrosol found mostly in the roots of Rhodiola spp. It
exhibits diverse biological and pharmacological properties. In the last decade, enormous …

Quantitative determination of salidroside in rat plasma by on-line solid-phase extraction integrated with high-performance liquid chromatography/electrospray …

YW Chang, HT Yao, SH Hsieh, TJ Lu, TK Yeh - Journal of Chromatography …, 2007 - Elsevier
A method for the quantification of salidroside, a major biologically active compound in
Rhodiola, in rat plasma by on-line SPE LC/MS/MS in negative electrospray mode was …

Protective effect of salidroside against H2O2-induced cell apoptosis in primary culture of rat hippocampal neurons

X Chen, Q Zhang, Q Cheng, F Ding - Molecular and cellular biochemistry, 2009 - Springer
Salidroside, a phenylpropanoid glycoside separated from a medicinal plant Rhodiola rosea,
has been documented to have protective effects on neuronal cells in vitro. This study …

Neuroprotective effects of salidroside administration in a mouse model of Alzheimer's disease

Q Li, J Wang, Y Li, X Xu - Molecular Medicine Reports, 2018 - spandidos-publications.com
Salidroside administration improves memory in different models of learning. However, its
influence on models of Alzheimer's disease (AD) has not been widely studied. In the present …

Pharmacokinetics, tissue distribution, and excretion of salidroside in rats

Y Zhang, L Li, L Lin, J Liu, Z Zhang, D Xu… - Planta …, 2013 - thieme-connect.com
The present study investigated the pharmacokinetics, excretion, and tissue distribution of
salidroside, a main active constituent in the roots of Rhodiola species. The plasma …