Erlotinib versus gemcitabine/cisplatin in Chinese patients with EGFR mutation-positive advanced non-small-cell lung cancer: Crossover extension and post-hoc …

YL Wu, C Zhou, S Lu, S Qin, H Pan, G Wu, Y Cheng… - Lung Cancer, 2019 - Elsevier
Objectives Sequential combination of epidermal growth factor receptor (EGFR)-tyrosine
kinase inhibitors (TKIs) and chemotherapy has shown greater benefits than either treatment …

[HTML][HTML] An open label phase II study evaluating first-line EGFR tyrosine kinase inhibitor erlotinib in non-small cell lung cancer patients with tumors showing high …

E Szutowicz-Zielinska, K Konopa, A Kowalczyk… - Oncotarget, 2017 - ncbi.nlm.nih.gov
An open label phase II study evaluating first-line EGFR tyrosine kinase inhibitor erlotinib in
non-small cell lung cancer patients with tumors showing high EGFR gene copy number - PMC …

Salvage treatment with erlotinib after gefitinib failure in advanced non‐small‐cell lung cancer patients with poor performance status: A matched‐pair case–control …

D Luo, M Huang, X Zhang, M Yu, B Zou, Y Li… - Thoracic …, 2012 - Wiley Online Library
Purpose: Gefitinib plays an important role in non‐small‐cell lung cancer (NSCLC) treatment;
however, progression of the disease occurs in most patients even after an initial response …

[HTML][HTML] Phase II study of erlotinib plus tivantinib (ARQ 197) in patients with locally advanced or metastatic EGFR mutation-positive non-small-cell lung cancer just after …

K Azuma, T Hirashima, N Yamamoto, I Okamoto… - ESMO open, 2016 - Elsevier
Background Patients with epidermal growth factor receptor (EGFR) activation mutation-
positive non-small-cell lung cancer (NSCLC) respond well to EGFR tyrosine kinase …

Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a …

R Rosell, E Carcereny, R Gervais… - The lancet …, 2012 - thelancet.com
Background Erlotinib has been shown to improve progression-free survival compared with
chemotherapy when given as first-line treatment for Asian patients with non-small-cell lung …

A randomized phase II study comparing erlotinib with or without bevacizumab in patients with advanced non–small cell lung cancer (NSCLC) with EGFR mutation.

Y Lee, HR Kim, MH Hong, KH Lee, KU Park, GK Lee… - 2022 - ascopubs.org
9107 Background: Synergistic anti-tumor effect of double blocking EGFR and VEGF
pathways is proven by preclinical and clinical data. This study evaluated whether an …

A phase II study of erlotinib monotherapy in pre-treated non-small cell lung cancer without EGFR gene mutation who have never/light smoking history: re-evaluation of …

Y Matsumoto, M Maemondo, Y Ishii, K Okudera… - Lung Cancer, 2014 - Elsevier
Objectives Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors are
particularly effective in non-small cell lung cancer (NSCLC) patients harboring active EGFR …

[HTML][HTML] A phase II trial of erlotinib monotherapy in pretreated patients with advanced non-small cell lung cancer who do not possess active EGFR mutations: Okayama …

H Yoshioka, K Hotta, K Kiura, N Takigawa… - Journal of Thoracic …, 2010 - Elsevier
Backgrounds Efficacy of gefitinib therapy strongly depends on epidermal growth factor
receptor (EGFR)-mutation status in Asian patients with non-small cell lung cancer. Recently …

Outcomes and prognostic factors in patients with EGFR mutant metastatic non-small cell lung cancer who treated with Erlotinib

İ DOĞAN, N Khanmammadov… - Clinical Cancer …, 2022 - avesis.istanbul.edu.tr
The study's goal is to evaluate the effectiveness of erlotinib in patients with EGFR mutant
metastatic non-small cell lung cancer (mNSCLC). The patient's medical data were analyzed …

Combination of gefitinib and olaparib versus gefitinib alone in EGFR mutant non-small-cell lung cancer (NSCLC): A multicenter, randomized phase II study (GOAL)

R Garcia-Campelo, O Arrieta, B Massuti… - Lung Cancer, 2020 - Elsevier
Objectives Progression-free survival (PFS) and response rate to epidermal growth factor
receptor (EGFR) tyrosine kinase inhibitors (TKIs) varies in patients with non-small-cell lung …