The improvement of oral bioavailability of poorly water soluble drug can be considered as
one of the greatest challenges in drug formulation. In recent years today, up to 90% of all …

Objective: Development and characterization of self-nanoemulsifying drug delivery system
for sertraline hydrochloride (SNEDDS). Methods: Solubility of sertraline hydrochloride in …

Background: The formulation and development of new chemical entities has the major
challenge of low solubility. A fraction of newly manufactured drugs (40%) have poor …

Background: Satranidazole is an antiprotozoal and antibacterial drug which falls under class
II drug as per biopharmaceutical classification systems having poor aqueous solubility. Aim …

In the current research work, losartan potassium (LP) loaded Self Emulsifying Drug Delivery
System (SEDDS) was formulated using various ratios of lipids, surfactants and co …

Repaglinide a BCS class II poorly water soluble drug was formulated into lipid drug delivery
system of self microemulsifying delivery system (SMEDDS). Surfactants and oil was selected …

The most common route of the drug administration is oral route despite the fact that most
drugs have low oral aqueous solubility and bioavailability especially for BCS class II and …

Clozapine is an atypical antipsychotic drug that exhibits low bioavailability (> 27%) due to
poor solubility and higher hepatic metabolism. The present investigation was aimed to …

The SMEDDS are the isotropic mixture of oil, surfactant and co-surfactant. SMEDDS solve
the problem of all BCS class of drug such as solubility, high molecular weight, pre systemic …