Treatment of Vitamin B12–Deficiency Anemia: Oral versus Parenteral Therapy

LA Lane, C Rojas-Fernandez - Annals of Pharmacotherapy, 2002 - journals.sagepub.com
OBJECTIVE: To evaluate the use of oral cyanocobalamin therapy in the treatment of
cobalamin (vitamin B12)–deficient anemia. DATA SOURCES: Primary and review articles …

Efficacy of short‐term oral cobalamin therapy for the treatment of cobalamin deficiencies related to food‐cobalamin malabsorption: a study of 30 patients

E Andres, G Kaltenbach, E Noel… - Clinical & Laboratory …, 2003 - Wiley Online Library
Background: It has been suggested that oral cobalamin (vitamin B12) therapy may be an
effective therapy for treating cobalamin deficiencies related to food‐cobalamin …

Efficacy of oral cobalamin (vitamin B12) therapy

E Andrès, H Fothergill, M Mecili - Expert opinion on …, 2010 - Taylor & Francis
Importance of the field: Cobalamin (vitamin B12) deficiency is particularly common in the
elderly (> 15%). Management of cobalamin deficiency with cobalamin injections is well …

Oral cobalamin (vitamin B12) treatment. An update

E Andrès, N Dali‐Youcef, T Vogel… - … journal of laboratory …, 2009 - Wiley Online Library
The objective of this review was to evaluate oral cobalamin (vitamin B12) therapy in adult
and elderly patients, from the perspective of a hematologist. PubMed was systematically …

Oral cobalamin therapy for the treatment of patients with food-cobalamin malabsorption

E Andrès, JE Kurtz, AE Perrin, F Maloisel… - The American journal of …, 2001 - Elsevier
BACKGROUND: The standard treatment for cobalamin (vitamin B12) deficiency involves
regular intramuscular cobalamin injection. It has been suggested that oral cobalamin …

Replacement therapy for vitamin B12 deficiency: comparison between the sublingual and oral route

A Sharabi, E Cohen, J Sulkes… - British journal of clinical …, 2003 - Wiley Online Library
Aims To compare the efficacy of sublingual and oral administration of 500 µg of cobalamin in
subjects with cobalamin deficiency. Materials and results Thirty subjects with low serum …

An update on cobalamin deficiency in adults

N Dali-Youcef, E Andrès - QJM: An International Journal of …, 2009 - academic.oup.com
Cobalamin (vitamin B12) deficiency is particularly common in the elderly (> 65 years of age),
but is often unrecognized because of its subtle clinical manifestations; although they can be …

Effective treatment of cobalamin deficiency with oral cobalamin

AM Kuzminski, EJ Del Giacco, RH Allen… - Blood, The Journal …, 1998 - ashpublications.org
Because cobalamin deficiency is routinely treated with parenteral cobalamin, we
investigated the efficacy of oral therapy. We randomly assigned 38 newly diagnosed …

Vitamin B12 replacement. To B12 or not to B12?

MD Delva - Canadian family physician, 1997 - ncbi.nlm.nih.gov
OBJECTIVE: To review the evidence for an expanded approach to identifying and treating
patients with cobalamin deficiency. Controversy surrounds this issue. Some authors claim …

Effects of oral crystalline cyanocobalamin 1000 μg/d in the treatment of pernicious anemia: an open-label, prospective study in ten patients

E Andrès, NH Loukili, E Noel, F Maloisel… - Current therapeutic …, 2005 - Elsevier
BACKGROUND:: Standard treatment of cobalamin (vitamin B12) deficiency involvesregular
(1000 μg/mo) IM cyanocobalamin administration. It has been suggested that high-dose (> …