The investigation of the prenatal and postnatal alcohol exposure-induced neurodegeneration in rat brain: protection by betaine and/or omega-3

K Kusat Ol, G Kanbak, A Oğlakcı Ilhan… - Child's Nervous …, 2016 - Springer
Purpose We aim to study the effect of neurodegeneration on the brain of rat pups caused by
prenatal and postnatal ethanol exposure with modified liquid diet to elucidate protective …

Fetal alcohol spectrum disorders and abnormal neuronal plasticity

AE Medina - The Neuroscientist, 2011 - journals.sagepub.com
The ingestion of alcohol during pregnancy can result in a group of neurobehavioral
abnormalities collectively known as fetal alcohol spectrum disorders (FASD). During the past …

[HTML][HTML] Glia and neurodevelopment: focus on fetal alcohol spectrum disorders

M Guizzetti, X Zhang, C Goeke, DP Gavin - Frontiers in pediatrics, 2014 - frontiersin.org
During the last 20 years, new and exciting roles for glial cells in brain development have
been described. Moreover, several recent studies implicated glial cells in the pathogenesis …

Acetaldehyde‐mediated neurotoxicity: relevance to fetal alcohol spectrum disorders

M Tong, L Longato, QGL Nguyen… - Oxidative Medicine …, 2011 - Wiley Online Library
Ethanol‐induced neuro‐developmental abnormalities are associated with impaired insulin
and IGF signaling, and increased oxidative stress in CNS neurons. We examined the roles …

Retinoic acid signaling reduction recapitulates the effects of alcohol on embryo size

N Shukrun, Y Shabtai, G Pillemer, A Fainsod - Genesis, 2019 - Wiley Online Library
Intrauterine growth restriction (IUGR) is commonly observed in human pregnancies and can
result in severe clinical outcomes. IUGR is observed in Fetal Alcohol Syndrome (FAS) …

[HTML][HTML] Nutrition implications for fetal alcohol spectrum disorder

JK Young, HE Giesbrecht, MN Eskin, M Aliani… - Advances in nutrition, 2014 - Elsevier
Prenatal alcohol exposure produces a multitude of detrimental alcohol-induced defects in
children collectively known as fetal alcohol spectrum disorder (FASD). Children with FASD …

Prenatal choline supplementation during mouse pregnancy has differential effects in alcohol‐exposed fetal organs

ST Kwan, DK Ricketts, BH Presswood… - Alcoholism: Clinical …, 2021 - Wiley Online Library
Background Fetal alcohol spectrum disorders (FASD) are preventable adverse outcomes
consequent to prenatal alcohol exposure. Supplemental choline confers neuroprotection to …

High‐throughput transcriptome sequencing identifies candidate genetic modifiers of vulnerability to fetal alcohol spectrum disorders

A Garic, ME Berres, SM Smith - Alcoholism: Clinical and …, 2014 - Wiley Online Library
Background Fetal alcohol spectrum disorders (FASD) is a leading cause of
neurodevelopmental disability. Genetic factors can modify vulnerability to FASD, but these …

[HTML][HTML] The universal and primary prevention of foetal alcohol spectrum disorders (FASD): a systematic review

B Jacobsen, C Lindemann, R Petzina, U Verthein - Journal of Prevention, 2022 - Springer
Foetal alcohol spectrum disorder (FASD) comprises multiple neurodevelopmental disorders
caused by alcohol consumption during pregnancy. With a global prevalence rate of 7.7 per …

Resveratrol restores Nrf2 level and prevents ethanol-induced toxic effects in the cerebellum of a rodent model of fetal alcohol spectrum disorders

A Kumar, CK Singh, HA LaVoie, DJ DiPette… - Molecular …, 2011 - ASPET
In humans, ethanol exposure during pregnancy produces a wide range of abnormalities in
infants collectively known as fetal alcohol spectrum disorders (FASD). Neuronal …