[图书][B] Translational research methods for diabetes, obesity and cardiometabolic drug development: a focus on early phase clinical studies
AJ Krentz, L Heinemann, M Hompesch - 2014 - Springer
As editors, we combine backgrounds anchored in the academic diabetes research
environment with extensive experience of the professionalism of the biopharmaceutical …
environment with extensive experience of the professionalism of the biopharmaceutical …
Approaching treatment of the insulin resistance syndrome
ZT Bloomgarden - Metabolic Syndrome and Related Disorders, 2005 - liebertpub.com
Insulin Resistance Syndrome (IRS), discussed effects of lifestyle modification on vascular
reactivity and endothelial function in the IRS, pointing out that this represents early …
reactivity and endothelial function in the IRS, pointing out that this represents early …
The impact of dietary factors on glycemic control, insulin sensitivity and secretion in the first years after diagnosis of diabetes
KS Weber, AE Buyken, B Nowotny… - Experimental and …, 2016 - thieme-connect.com
Background: Dietary factors play an important role in the prevention of diabetes mellitus. We
tested the hypothesis that dietary factors related to diabetes onset also associate with its …
tested the hypothesis that dietary factors related to diabetes onset also associate with its …
How to measure adipose tissue insulin sensitivity
E Søndergaard, AE Espinosa De Ycaza… - The Journal of …, 2017 - academic.oup.com
Abstract Context and Objective: Adipose tissue insulin resistance may cause hepatic and
skeletal muscle insulin resistance by releasing excess free fatty acids (FFAs). Because no …
skeletal muscle insulin resistance by releasing excess free fatty acids (FFAs). Because no …
Diabetes risk in relation to weight loss, weight stability and degree of obesity-The Swedish Obese Subjects (SOS) study
M Peltonen, L Sjostrom, L Carlsson - Endocrine Abstracts, 2012 - endocrine-abstracts.org
Objective: Among severely obese individuals, surgically induced weight loss reduces the
risk for type 2 diabetes. The aim of this study was to analyse the incidence and remission of …
risk for type 2 diabetes. The aim of this study was to analyse the incidence and remission of …
Intensive lifestyle changes are necessary to improve insulin sensitivity: a randomized controlled trial
KA McAuley, SM Williams, JI Mann, A Goulding… - Diabetes …, 2002 - Am Diabetes Assoc
OBJECTIVE—The extent to which lifestyle must be altered to improve insulin sensitivity has
not been established. This study compares the effect on insulin sensitivity of current dietary …
not been established. This study compares the effect on insulin sensitivity of current dietary …
Banting Memorial Lecture 2021—Banting, banting, banter and bravado: Convictions meet evidence in the scientific process: Diabetes UK Professional Conference, 27 …
MEJ Lean - Diabetic Medicine, 2021 - Wiley Online Library
This personal account presents some glimpses into the clinical research processes which
have made radical changes to our understanding of disease and treatment, and some …
have made radical changes to our understanding of disease and treatment, and some …
Obesity and diabetes
H Hauner - Textbook of diabetes, 2017 - Wiley Online Library
Obesity has become a worldwide epidemic and is mainly driven by environmental and
lifestyle changes characterized by an energy‐dense, hypercaloric diet, and a decrease in …
lifestyle changes characterized by an energy‐dense, hypercaloric diet, and a decrease in …
Effects of type 2 diabetes and insulin on whole-body, splanchnic, and leg protein metabolism
Context: Type 2 diabetes (T2D) is characterized by insulin resistance to glucose metabolism.
Most studies suggest that protein metabolism is unaffected by T2D, but regional protein …
Most studies suggest that protein metabolism is unaffected by T2D, but regional protein …
[引用][C] CHANGES IN BODY COMPOSITION THROUGH A LIFESTYLE INTERVENTION PROGRAM LEAD TO REMISSION OF TYPE 2 DIABETES, PREDIABETES …
J Iglesies-Grau, A Paradis… - Canadian …, 2023 - canadianjournalofdiabetes.com
BACKGROUND Type 2 diabetes (T2D), prediabetes (Pred), and insulin resistance (IR) were
previously believed to be irreversible conditions. However, thanks to numerous studies on …
previously believed to be irreversible conditions. However, thanks to numerous studies on …