The delivery of drugs through the oral route is regarded as most optimal to achieve desired
therapeutic effects and patient compliance. However, poor pharmacokinetic profiles of oral …

Oral delivery of drugs with poor aqueous solubility and poor enzymatic and/or metabolic
stability is very challenging. However, the advent of nanotechnology has revolutionized the …

Nanotechnology has been applied to the oral drug delivery for enhancing bioavailability
after oral administration. Numerous forms of reported nanomedicines are classified as lipid …

The field of nanomedicine offers promising new drug delivery systems with enhanced
properties. The literature has reported on the development of various nanomedicines that …

Many new chemical entities have limited water solubility and therefore show low and/or
variable oral bioavailability. Among the various strategies to overcome this challenge …

To date, various nanodrug systems have been developed for different routes of
administration, which include dendrimers, nanocrystals, emulsions, liposomes, solid lipid …

This chapter summarizes the types of nano drugs, their synthesis, formulation,
characterization, and applications, with the most important administration routes. To achieve …

Poor aqueous solubility represents a major hurdle in achieving adequate oral bioavailability
for a large percentage of drug compounds in drug development nowadays. Nanosizing …

Background In recent decades, there has been a considerable increase in the number of
nanomedicine-based formulations, and their advantages, including controlled/targeted drug …

The increasing frequency at which poorly soluble new chemical entities are being
discovered raises concerns in the pharmaceutical industry about drugability associated with …