Ethanol exposure during development, and brain oxidative stress

J Gil-Mohapel, CD Bianco, PA Cesconetto… - Neuroscience of …, 2019 - Elsevier
Ethanol exposure during pregnancy can produce a variety of central nervous system
abnormalities in the offspring, resulting in a broad spectrum of cognitive and behavioral …

The role of oxidative stress in fetal alcohol spectrum disorders

PS Brocardo, J Gil-Mohapel, BR Christie - Brain research reviews, 2011 - Elsevier
The ingestion of alcohol/ethanol during pregnancy can result in abnormal fetal development
in both humans and a variety of experimental animal models. Depending on the pattern of …

[HTML][HTML] An overview of current advances in perinatal alcohol exposure and pathogenesis of fetal alcohol spectrum disorders

X Zeng, Y Cai, M Wu, H Chen, M Sun… - Journal of …, 2024 - Springer
The adverse use of alcohol is a serious global public health problem. Maternal alcohol
consumption during pregnancy usually causes prenatal alcohol exposure (PAE) in the …

Acetaldehyde‐mediated neurotoxicity: relevance to fetal alcohol spectrum disorders

M Tong, L Longato, QGL Nguyen… - Oxidative Medicine …, 2011 - Wiley Online Library
Ethanol‐induced neuro‐developmental abnormalities are associated with impaired insulin
and IGF signaling, and increased oxidative stress in CNS neurons. We examined the roles …

[HTML][HTML] Oxidative Effects in Early Stages of Embryo Development Due to Alcohol Consumption

D González-Flores, A Márquez, I Casimiro - International Journal of …, 2024 - mdpi.com
Alcohol, a widely consumed drug, exerts significant toxic effects on the human organism.
This review focuses on its impact during fetal development, when it leads to a spectrum of …

[HTML][HTML] Fetal alcohol spectrum disorder: potential role of endocannabinoids signaling

BS Basavarajappa - Brain sciences, 2015 - mdpi.com
One of the unique features of prenatal alcohol exposure in humans is impaired cognitive
and behavioral function resulting from damage to the central nervous system (CNS), which …

[HTML][HTML] Aberrant behavioral and neurobiologic profiles in rodents exposed to ethanol or red wine early in development

S De Nicolò, V Carito, M Fiore, G Laviola - Current Developmental …, 2014 - Springer
Alcohol intake by women before planning a pregnancy, during pregnancy, and/or during
lactation induces brain, behavioral, and physical abnormalities in the fetus, which are known …

The effects of ethanol exposure during distinct periods of brain development on oxidative stress in the adult rat brain

PS Brocardo, J Gil‐Mohapel, R Wortman… - Alcoholism: Clinical …, 2017 - Wiley Online Library
Background The consumption of alcohol during pregnancy can result in abnormal fetal
development and impaired brain function in humans and experimental animal models …

Ethanol influences on Bax translocation, mitochondrial membrane potential, and reactive oxygen species generation are modulated by vitamin E and brain‐derived …

MB Heaton, M Paiva… - Alcoholism: Clinical and …, 2011 - Wiley Online Library
Background: This study investigated ethanol influences on intracellular events that
predispose developing neurons toward apoptosis and the capacity of the antioxidant α …

Mechanisms involved in central nervous system dysfunctions induced by prenatal ethanol exposure

C Guerri - Neurotoxicity research, 2002 - Springer
Clinical and experimental evidence has demonstrated that ethanol is a teratogen, and that
its consumption during pregnancy induces harmful effects on the developing foetus that …