Background Adverse reactions to naloxone, such as withdrawal symptoms and aggression,
are widely recognised in the literature by pharmaceutical manufacturers and clinical …

Background Opioid overdose is a major cause of mortality, but injury and fatal outcomes can
be prevented by timely administration of the opioid antagonist naloxone. Pre-provision of …

Heroin overdose deaths have increased alarmingly in Chicago over the past decade.
Naloxone, an opioid antagonist with no abuse potential, has been used to reverse opiate …

Background Drug overdose is the leading cause of death after release from prison, and this
risk is significantly higher among women compared to men. Within the first 2 weeks after …

Overdose due to opioid abuse is an ever increasing problem, especially in the United
States, with the last few years seeing a dramatic rise in the number of synthetic opioid …

BACKGROUND: In response to the high rates of opiate-related overdoses and deaths in the
United States, a number of overdose prevention programmes have been implemented that …

[Editor's note: What is especially interesting about this effort by New York is that it took one
person to look past the law to get the ball rolling, and then it took the efforts of many inside …

Importance The US opioid crisis was deemed a public health emergency in 2017. More than
130 individuals in the US die daily as a result of unintentional opioid overdose deaths …

The United States is in the midst of a prolonged and growing epidemic of accidental and
preventable deaths associated with overdoses of licit and illicit opioids. For more than 3 …

Naloxone is a specific, high affinity opioid antagonist that has been used to treat suspected
or confirmed overdose for more than 40 years. Naloxone use was initially confined to an …