Perspectives on the complex links between depression and dementia

A Hakim - Frontiers in Aging Neuroscience, 2022 - frontiersin.org
This review highlights that depression is a growing health problem for the individual, and
because of its high frequency in most societies, a growing burden on health care budgets …

Pathways connecting late-life depression and dementia

C Linnemann, UE Lang - Frontiers in pharmacology, 2020 - frontiersin.org
Late-life depression is associated with significant cognitive impairment. Meta-analyses
showed that depression is associated with an increased risk for Alzheimer's disease (AD) …

Overlay of late-life depression and cognitive impairment

R Aziz, D Steffens - Focus, 2017 - Am Psychiatric Assoc
This article appraises several facets of the linkage between depression and cognitive
impairment, including dementia, mild cognitive impairment, and vascular dementia. Potential …

Depression, dementia and immune dysregulation

S Hayley, AM Hakim, PR Albert - Brain, 2021 - academic.oup.com
Major depression is a prevalent illness that increases the risk of several neurological
conditions. These include stroke, cardiovascular disease, and dementia including …

[PDF][PDF] Aging, depression, and dementia: The inflammatory process.

MP Carrera-González, V Cantón-Habas, M Rich-Ruiz - 2022 - ruja.ujaen.es
Population aging that we are currently witnessing has led to an increase in chronic age-
related diseases, with dementia and depression being highlighted. Several studies establish …

The association between late-life depression, mild cognitive impairment and dementia: is inflammation the missing link?

AP Hermida, WM McDonald, K Steenland… - Expert review of …, 2012 - Taylor & Francis
Depression, mild cognitive impairment (MCI) and dementia are highly prevalent conditions
that are increasing exponentially with similarly expanding social, medical and economic …

Microvascular contribution to late-onset depression: mechanisms, current evidence, association with other brain diseases, and therapeutic perspectives

JP Empana, P Boutouyrie, C Lemogne, X Jouven… - Biological …, 2021 - Elsevier
Depression is common in older individuals and is associated with high disability and
mortality. A major problem is treatment resistance:> 50% of older patients do not respond to …

Perfusion deficits, inflammation and aging precipitate depressive behaviour

A Popa-Wagner, AM Buga, AA Tica, CV Albu - Biogerontology, 2014 - Springer
Major depressive disorder (MDD) is a severe psychiatric illness that is associated with
significant morbidity and mortality. Despite advances in the treatment of major depression …

Inflammation, depression and dementia: are they connected?

BE Leonard - Neurochemical research, 2007 - Springer
Chronic inflammation is now considered to be central to the pathogenesis not only of such
medical disorders as cardiovascular disease, multiple sclerosis, diabetes and cancer but …

Depression and risk of developing dementia

AL Byers, K Yaffe - Nature Reviews Neurology, 2011 - nature.com
Depression is highly common throughout the life course and dementia is common in late life.
Depression has been linked with dementia, and growing evidence implies that the timing of …