Mitochondrial redox imaging for cancer diagnostic and therapeutic studies
Mitochondrial redox states provide important information about energy-linked biological
processes and signaling events in tissues for various disease phenotypes including cancer …
processes and signaling events in tissues for various disease phenotypes including cancer …
Quantitative redox imaging biomarkers for studying tissue metabolic state and its heterogeneity
NAD+/NADH redox state has been implicated in many diseases such as cancer and
diabetes as well as in the regulation of embryonic development and aging. To …
diabetes as well as in the regulation of embryonic development and aging. To …
REDOX IMAGING OF THE p53-DEPENDENT MITOCHONDRIAL REDOX STATE IN COLON CANCER EX VIVO
The mitochondrial redox state and its heterogeneity of colon cancer at tissue level have not
been previously reported. Nor has how p53 regulates mitochondrial respiration been …
been previously reported. Nor has how p53 regulates mitochondrial respiration been …
Quantitative mitochondrial redox imaging of breast cancer metastatic potential
HN Xu, S Nioka, JD Glickson… - Journal of biomedical …, 2010 - spiedigitallibrary.org
Predicting tumor metastatic potential remains a challenge in cancer research and clinical
practice. Our goal was to identify novel biomarkers for differentiating human breast tumors …
practice. Our goal was to identify novel biomarkers for differentiating human breast tumors …
Quantitative redox scanning of tissue samples using a calibration procedure
HN Xu, B Wu, S Nioka, B Chance… - Journal of innovative …, 2009 - World Scientific
The fluorescence properties of reduced nicotinamide adenine dinucleotide (NADH) and
oxidized flavoproteins (Fp) including flavin adenine dinucleotide (FAD) in the respiratory …
oxidized flavoproteins (Fp) including flavin adenine dinucleotide (FAD) in the respiratory …
Imaging mitochondrial redox potential and its possible link to tumor metastatic potential
LZ Li - Journal of bioenergetics and biomembranes, 2012 - Springer
Cellular redox states can regulate cell metabolism, growth, differentiation, motility, apoptosis,
signaling pathways, and gene expressions etc. A growing body of literature suggest the …
signaling pathways, and gene expressions etc. A growing body of literature suggest the …
Optical redox imaging of lonidamine treatment response of melanoma cells and xenografts
Purpose Fluorescence of co-enzyme reduced nicotinamide adenine dinucleotide (NADH)
and oxidized flavoproteins (Fp) provides a sensitive measure of the mitochondrial redox …
and oxidized flavoproteins (Fp) provides a sensitive measure of the mitochondrial redox …
FLUORESCENT IMAGES OF MITOCHONDRIAL REDOX STATES IN IN SITU MOUSE HYPOXIC ISCHEMIC INTESTINES
We have imaged mitochondrial oxidation–reduction states by taking a ratio of mitochondrial
fluorophores: NADH (reduced nicotinamide adenine dinucleotide) to Fp (oxidized …
fluorophores: NADH (reduced nicotinamide adenine dinucleotide) to Fp (oxidized …
Optical redox imaging indices discriminate human breast cancer from normal tissues
Our long-term goal was to investigate the potential of incorporating redox imaging technique
as a breast cancer (BC) diagnosis component to increase the positive predictive value of …
as a breast cancer (BC) diagnosis component to increase the positive predictive value of …
Calibration of redox scanning for tissue samples
HN Xu, B Wu, S Nioka, B Chance… - Optical Tomography and …, 2009 - spiedigitallibrary.org
The fluorescence properties of reduced nicotinamide adenine dinucleotide (NADH) and
oxidized flavoproteins (Fp) such as flavin adenine dinucleotide (FAD) in the respiratory …
oxidized flavoproteins (Fp) such as flavin adenine dinucleotide (FAD) in the respiratory …