Three types of early termination Of antidepressant Page 1 International Cliniai shphrol 093),
83536 Three types of early termination Of antidepressant drug treatment M Linden M …

Background: Stopping antidepressants commonly causes withdrawal symptoms, which can
be severe and long-lasting. National Institute for Health and Care Excellence (NICE) …

Objective: A substantial number of patients who respond to antidepressants experience a
relapse despite ongoing pharmacotherapy. The return of symptoms has been interpreted as …

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Use of antidepressants has recently increased, mainly caused by the increase of long-term
users. Although evidence-based indications for long-term use are lacking, it is assumed that …

The treatment of depression in patients who rapidly cycle once they receive antidepressant
medication is a difficult clinical problem. Hurowitz and Liebowitz presented six patients with …

Sudden or tapered withdrawal from treatment with antidepressants, including monoamine
oxidase inhibitors (MAOIs), tricyclic antidepressants (TCAs), and serotonin selective …

Sir, Having shown that clozapine induces a discontinuation syndrome in rats (Goudie et al.,
1999), some years ago we reviewed the clinical significance of this syndrome (Goudie …

Depression is increasingly recognized as a highly recurrent and potentially chronic illness
that imposes a substantial burden on individuals, families, and society. Evidence indicates …

Discontinuation reactions are a group of characteristic physical and psychological symptoms
that commence shortly after stopping or, less commonly, after reducing the dose of an …