Obstructive sleep apnea and cerebral white matter change: a systematic review and meta-analysis

BL Ho, PT Tseng, CL Lai, MN Wu, MJ Tsai, CF Hsieh… - Journal of …, 2018 - Springer
Obstructive sleep apnea (OSA) can cause sleep fragmentation and intermittent hypoxemia,
which are linked to oxidative stress. White matter changes (WMCs) representing …

Non breathing-related sleep fragmentation and imaging markers in patients with atherosclerotic cerebral small vessel disease (CSVD): a cross-sectional case-control …

J Wang, X Chen, J Liao, L Zhou, H Han, J Tao, Z Lu - BMC neurology, 2020 - Springer
Background Sleep fragmentation was shown to be positively associated with cognitive
impairment in patients with cerebral small vessel disease (CSVD); however, the underlying …

Nocturnal hypoxemia is associated with white matter hyperintensities in patients with a minor stroke or transient ischemic attack

SK Patel, PJ Hanly, EE Smith, W Chan… - Journal of Clinical …, 2015 - jcsm.aasm.org
Study Objectives: Obstructive sleep apnea (OSA) is a risk factor for stroke, which is
modulated by accompanying nocturnal hypoxemia. White matter hyperintensities (WMH) …

Case control study of cerebrovascular damage defined by magnetic resonance imaging in patients with OSA and normal matched control subjects

CWH Davies, JH Crosby, RL Mullins, ZC Traill… - Sleep, 2001 - academic.oup.com
Study Objectives To assess whether MRI detectable evidence of silent cerebrovascular
disease is more prevalent in patients with obstructive sleep apnea (OSA) when compared to …

Associations of sleep apnea risk and oxygen desaturation indices with cerebral small vessel disease burden in patients with stroke

X Liu, DCL Lam, HKF Mak, MSM Ip, KK Lau - Frontiers in Neurology, 2022 - frontiersin.org
Background Obstructive sleep apnea (OSA) is associated with cerebral small vessel disease
(CSVD). Nonetheless, whether OSA-risk determined by a simple screening questionnaire or …

Sleep apnea, sleep duration and brain MRI markers of cerebral vascular disease and Alzheimer's disease: the atherosclerosis risk in communities study (ARIC)

PL Lutsey, FL Norby, RF Gottesman, T Mosley… - PloS one, 2016 - journals.plos.org
Background A growing body of literature has suggested that obstructive sleep apnea (OSA)
and habitual short sleep duration are linked to poor cognitive function. Neuroimaging …

Cerebrovascular reactivity in young and old patients with obstructive sleep apnea

N Li, Y Liu, Y Zhao, X Wu, J Tong, Y Hua - Sleep medicine, 2020 - Elsevier
Objective Impaired cerebrovascular reactivity (CVR) in patients with obstructive sleep apnea
syndrome (OSAS) increases the risk of ischemic stroke. CVR also decreases with age in …

Sleep duration is associated with white matter hyperintensity volume in older adults: the Northern Manhattan Study

AR Ramos, C Dong, T Rundek… - Journal of sleep …, 2014 - Wiley Online Library
Self‐reports of long or short sleep durations have indicated an association with
cardiovascular morbidity and mortality, but there are limited data evaluating their association …

Sleep characteristics and risk of stroke and dementia: an observational and Mendelian randomization study

C Guo, EL Harshfield, HS Markus - Neurology, 2024 - AAN Enterprises
Background and Objectives Sleep disturbances are implicated as risk factors of both stroke
and dementia. However, whether these associations are causal and whether treatment of …

Effect of heart rate variability on the association between the apnea-hypopnea index and cerebral small vessel disease

OH Del Brutto, RM Mera, AF Costa, PR Castillo - Stroke, 2019 - Am Heart Assoc
Background and Purpose—The apnea-hypopnea index (AHI) is associated with cerebral
small vessel disease (cSVD), but pathogenesis of this association is elusive. We aimed to …