Cardiovascular aspects in obstructive sleep apnea syndrome–molecular issues, hypoxia and cytokine profiles

L Lavie, V Polotsky - Respiration, 2009 - karger.com
Obstructive sleep apnea syndrome (OSAS), which is a highly prevalent breathing disorder in
sleep, is an independent risk factor for cardiovascular morbidity and mortality. Results from …

[HTML][HTML] Lipid peroxides, superoxide dismutase and circulating IL-8 and GCP-2 in patients with severe obstructive sleep apnea: a pilot study

MA Alzoghaibi, ASO BaHammam - Sleep and Breathing, 2005 - Springer
Obstructive sleep apnea (OSA) is associated with cardiovascular morbidity and mortality and
many other physiological and immunological disorders. An increase in hypoxia due to OSA …

[HTML][HTML] Chronic intermittent hypoxia in obstructive sleep apnea: a narrative review from pathophysiological pathways to a precision clinical approach

G Labarca, J Gower, L Lamperti, J Dreyse… - Sleep and …, 2020 - Springer
Obstructive sleep apnea syndrome (OSAS) is a prevalent condition caused by dynamic
upper airway collapse during sleep. The pathological impact and consequences are due to …

Obstructive sleep apnea and inflammation: relationship to cardiovascular co-morbidity

BD Kent, S Ryan, WT McNicholas - Respiratory physiology & neurobiology, 2011 - Elsevier
Obstructive sleep apnoea syndrome (OSAS) is a highly prevalent disease and associated
with cardiovascular morbidity and mortality. The pathogenesis of cardiovascular …

Oxidative stress—a unifying paradigm in obstructive sleep apnea and comorbidities

L Lavie - Progress in cardiovascular diseases, 2009 - Elsevier
Obstructive sleep apnea (OSA), a highly prevalent breathing disorder in sleep, characterized
by intermittent and recurrent pauses in respiration, has emerged as an independent risk …

Molecular mechanisms of cardiovascular disease in OSAHS: the oxidative stress link

L Lavie, P Lavie - European Respiratory Journal, 2009 - Eur Respiratory Soc
Obstructive sleep apnoea/hypopnoea syndrome (OSAHS) is a highly prevalent breathing
disorder in sleep that is an independent risk factor for cardiovascular morbidity and mortality …

Cardiovascular disease in obstructive sleep apnoea syndrome: the role of intermittent hypoxia and inflammation

JF Garvey, CT Taylor… - European Respiratory …, 2009 - Eur Respiratory Soc
There is increasing evidence that intermittent hypoxia plays a role in the development of
cardiovascular risk in obstructive sleep apnoea syndrome (OSAS) through the activation of …

Oxidative stress mediated arterial dysfunction in patients with obstructive sleep apnoea and the effect of continuous positive airway pressure treatment

M Del Ben, M Fabiani, L Loffredo, L Polimeni… - BMC Pulmonary …, 2012 - Springer
Background Several studies suggest an increase of oxidative stress and a reduction of
endothelial function in obstructive sleep apnoea syndrome (OSAS). We assessed the …

Increased upper airway cytokines and oxidative stress in severe obstructive sleep apnoea

RJ Kimoff, Q Hamid, M Divangahi… - European …, 2011 - Eur Respiratory Soc
Inflammation may contribute to upper airway pathophysiology in obstructive sleep apnoea
(OSA). Our objective was to compare upper airway pro-inflammatory cytokine expression …

[PDF][PDF] Oxidative stress inflammation and endothelial dysfunction in obstructive sleep apnea

L Lavie - Frontiers in Bioscience-Elite, 2012 - academia.edu
Introduction 3. Association of OSA with cardiovascular morbidity 3.1. Prevailing mechanisms
4. Oxidative stress in OSA 4.1. Consequences of oxidative stress 4.2. Reactive oxygen …