Systemic inflammation: a key factor in the pathogenesis of cardiovascular complications in obstructive sleep apnoea syndrome?

S Ryan, CT Taylor… - Postgraduate medical …, 2009 - academic.oup.com
Obstructive sleep apnoea syndrome (OSAS) is a highly prevalent disease and is recognised
as a major public health burden. Large-scale epidemiological studies have demonstrated an …

Selective activation of inflammatory pathways by intermittent hypoxia in obstructive sleep apnea syndrome

S Ryan, CT Taylor, WT McNicholas - Circulation, 2005 - Am Heart Assoc
Background—Obstructive sleep apnea syndrome (OSAS), characterized by intermittent
hypoxia/reoxygenation (IHR), is an independent risk factor for cardiovascular disease. We …

Relationship of oxidative stress and endothelial dysfunction in sleep apnoea

B Jurado-Gamez, MC Fernandez-Marin… - European …, 2011 - Eur Respiratory Soc
The aim of the present study was to evaluate ischaemic reactive hyperaemia (IRH) in
obstructive sleep apnoea (OSA) and its relationship with oxidative stress. We studied 69 …

[HTML][HTML] Pathophysiological mechanisms and therapeutic approaches in obstructive sleep apnea syndrome

R Lv, X Liu, Y Zhang, N Dong, X Wang, Y He… - Signal transduction and …, 2023 - nature.com
Obstructive sleep apnea syndrome (OSAS) is a common breathing disorder in sleep in
which the airways narrow or collapse during sleep, causing obstructive sleep apnea. The …

Molecular signatures of obstructive sleep apnea in adults: a review and perspective

ES Arnardottir, M Mackiewicz, T Gislason, KL Teff… - Sleep, 2009 - academic.oup.com
The consequences of obstructive sleep apnea (OSA) are largely mediated by chronic
intermittent hypoxia and sleep fragmentation. The primary molecular domains affected are …

Increased 8-isoprostane and interleukin-6 in breath condensate of obstructive sleep apnea patients

GE Carpagnano, SA Kharitonov, O Resta… - Chest, 2002 - Elsevier
Study objectives Obstructive sleep apnea (OSA) is characterized by repeated episodes of
upper airways obstruction during sleep that result in episodes of hypoxia. An increase of …

Evidence for lipid peroxidation in obstructive sleep apnea

L Lavie, A Vishnevsky, P Lavie - Sleep, 2004 - academic.oup.com
Abstract Study Objectives: Obstructive sleep apnea syndrome (OSA) is associated with an
increased rate of cardiovascular morbidity, which has been suggested to be related to …

[HTML][HTML] Potential diagnostic and monitoring biomarkers of obstructive sleep apnea–Umbrella Review of Meta-analyses

P Fiedorczuk, A Polecka, M Walasek… - Journal of Clinical …, 2022 - mdpi.com
Obstructive sleep apnea (OSA) is a prevalent, underdiagnosed disease that imposes a
significant impact on the health and wellbeing of patients and a financial burden on …

Biomarkers of sleep apnea

SB Montesi, EK Bajwa, A Malhotra - Chest, 2012 - Elsevier
Obstructive sleep apnea (OSA) is a condition of repetitive upper airway collapse, which
occurs during sleep. Recent literature has emphasized the role of OSA in contributing to …

[HTML][HTML] Peripheral biomarkers to diagnose obstructive sleep apnea in adults: A systematic review and meta-analysis

LS Gaspar, A Santos-Carvalho, B Santos… - Sleep Medicine …, 2022 - Elsevier
Summary Background Obstructive Sleep Apnea (OSA) has been recognized as a major
health concern worldwide, given its increasing prevalence, difficulties in diagnosis and …